This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-PIAS2 Antibody
catalog :
MBS420333
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS420333
products type :
Antibody
products full name :
Goat anti-PIAS2 Antibody
products short name :
PIAS2
products name syn :
PIAS2; protein inhibitor of activated STAT; 2; MGC102682; MIZ1; PIASX-ALPHA; PIASX-BETA; SIZ2; miz; Msx-interacting-zinc finger; protein inhibitor of activated STAT X; ARIP3; Goat Anti-PIAS2 (aa185-196); PIAS2; protein inhibitor of activated STAT, 2; MGC102682; MIZ1; PIASX-ALPHA; PIASX-BETA; SIZ2; miz; Msx-interacting-zinc finger; protein inhibitor of activated STAT X; ARIP3
other names :
E3 SUMO-protein ligase PIAS2 isoform alpha; E3 SUMO-protein ligase PIAS2; E3 SUMO-protein ligase PIAS2; DAB2-interacting protein; zinc finger, MIZ-type containing 4; msx-interacting zinc finger protein; protein inhibitor of activated STAT X; androgen receptor-interacting protein 3; protein inhibitor of activated STAT, 2; Androgen receptor-interacting protein 3; ARIP3; DAB2-interacting protein; DIP; Msx-interacting zinc finger protein; Miz1; PIAS-NY protein; Protein inhibitor of activated STAT x; Protein inhibitor of activated STAT2
products gene name :
PIAS2
other gene names :
PIAS2; PIAS2; DIP; MIZ; MIZ1; SIZ2; ARIP3; PIASX; ZMIZ4; PIASX-BETA; PIASX-ALPHA; PIASX; ARIP3; DIP; Miz1
uniprot entry name :
PIAS2_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog
sequence length :
572
sequence :
KEAMKVSSQPCTKIE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Human Testis shows nuclear and extra-nuclear staining in spermatids. Recommended concentration, 3-5ug/ml. Western Blot: Preliminary experiments gave an approx 90kDa band in lysates of cell line A431after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 68.2kDa according to NP_004662.2. The 90kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence KEAMKVSSQPCTKIE, from the internal region of the protein sequence according to NP_775298.1; NP_004662.2. Corresponding Immunizing Peptide: Catalog #MBS428216
other info2 :
Important Note: This antibody is expected to recognise both reported isoforms (NP_775298.1 and NP_004662.2). No cross-reactivity expected with PIAS1, 3 and 4.
ncbi gi num :
27532984
ncbi acc num :
NP_775298.1
ncbi gb acc num :
NM_173206.3
ncbi mol weight :
45,057 Da
ncbi pathways :
IL12 Signaling Mediated By STAT4 Pathway 137936!!Jak-STAT Signaling Pathway 83077!!Jak-STAT Signaling Pathway 488!!Pathways In Cancer 83105!!Small Cell Lung Cancer Pathway 83118!!Small Cell Lung Cancer Pathway 530!!Sumoylation By RanBP2 Regulates Transcriptional Repression Pathway 138029!!TGF-beta Receptor Signaling Pathway 198774!!Ubiquitin Mediated Proteolysis Pathway 83056!!Ubiquitin Mediated Proteolysis Pathway 466
ncbi summary :
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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