catalog number :
MBS420327
products full name :
Goat anti-Glutathione peroxidase 2 (Int) Antibody
products short name :
Glutathione peroxidase 2
products name syn :
glutathione peroxidase 2 (gastrointestinal); HGNC:4554; GPX2; GI-GPx; GSHPX-GI; gastrointestinal glutathione peroxidase 2; GPRP; GSHPx-2; glutathione peroxidase 2; glutathione peroxidase-related protein 2; GPX2; glutathione peroxidase 2 (gastrointestinal); HGNC:4554; GI-GPx; GSHPX-GI; gastrointestinal glutathione peroxidase 2; GPRP; GSHPx-2; glutathione peroxidase 2; glutathione peroxidase-related protein 2
other names :
glutathione peroxidase 2; Glutathione peroxidase 2; glutathione peroxidase 2; gastrointestinal glutathione peroxidase; glutathione peroxidase-related protein 2; glutathione peroxidase 2 (gastrointestinal); Gastrointestinal glutathione peroxidase; Glutathione peroxidase-gastrointestinal; GPx-GI; GSHPx-GI; Glutathione peroxidase-related protein 2; GPRP-2
products gene name :
GPX2
other gene names :
GPX2; GPX2; GPRP; GPx-2; GI-GPx; GPRP-2; GPx-GI; GSHPx-2; GSHPX-GI; GPx-2; GSHPx-2; GPx-GI; GSHPx-GI; GPRP-2
uniprot entry name :
GPX2_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 24kDa band observed in Human Liver lysates (calculated MW of 21.9kDa according to NP_002074.2). Recommended concentration: 0.5-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-SLDGEKVDFN, from the internal region of the protein sequence according to NP_002074.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425929
products references :
McGrath-Morrow S, Lauer T, Yee M, Neptune E, Podowski M, Thimmulappa RK, O'Reilly M, Biswal S.; Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia.; Am J Physiol Lung Cell Mol Physiol. 2009 Apr; 296(4):L565-73.; Pubmed 19151108
ncbi acc num :
NP_002074.2
ncbi gb acc num :
NM_002083.3
ncbi mol weight :
21,954 Da
ncbi pathways :
Arachidonic Acid Metabolism Pathway 82991!!Arachidonic Acid Metabolism Pathway 685553!!Arachidonic Acid Metabolism Pathway 366!!Cellular Responses To Stress Pathway 645258!!Detoxification Of Reactive Oxygen Species Pathway 941400!!Folate Metabolism Pathway 198833!!Glutathione Metabolism Pathway 82973!!Glutathione Metabolism Pathway 198824!!Glutathione Metabolism Pathway 343!!Metabolism Pathway 477135
ncbi summary :
This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. The protein encoded by this locus contains a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]