This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-BLNK / SLP-65 Antibody
catalog :
MBS420310
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, enzyme immunoassay
product information
catalog number :
MBS420310
products type :
Antibody
products full name :
Goat anti-BLNK / SLP-65 Antibody
products short name :
BLNK/SLP-65
products name syn :
BLNK; SLP-65; B-cell linker; BASH; BLNK-s; Ly57; MGC111051; SLP65; B cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; OTTHUMP00000020167; Src homology 2 domain-containing leukocyte protein of 65 kDa; BLNK-S; LY57; OTTHUMP00000020168; BLNK; SLP-65; B-cell linker; BASH; BLNK-s; Ly57; MGC111051; SLP65; B cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; OTTHUMP00000020167; Src homology 2 domain-containing leukocyte protein of 65 kDa; BLNK-S; LY57; OTTHUMP00000020168
other names :
B-cell linker protein isoform 1; B-cell linker protein; B-cell linker protein; B-cell activation; B cell linker protein; cytoplasmic adapter protein; B cell adaptor containing SH2 domain; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Src homology 2 domain-containing leukocyte protein of 65 kDa; B-cell linker; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa; SLP-65
products gene name :
BLNK
other gene names :
BLNK; BLNK; bca; AGM4; BASH; LY57; SLP65; BLNK-S; SLP-65; BASH; SLP65; SLP-65
uniprot entry name :
BLNK_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
sequence length :
456
sequence :
KDSTRLKYAVKVS
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 70kDa band observed in lysates of cell line Daudi (calculated MW of 50.5kDa according to NP_037446.1). The observed molecular weight corresponds to how SLP-65 is expected to run. However, when transiently expressed in HEK293, a 50kDa band is observed. Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-KDSTRLKYAVKVS, from the C Terminus of the protein sequence according to NP_037446.1; NP_001107566.1. Corresponding Immunizing Peptide: Catalog #MBS426101
other info2 :
Important Note: This antibody is expected to recognize both reported isoforms (NP_037446.1; NP_001107566.1).
ncbi gi num :
7019535
ncbi acc num :
NP_037446.1
ncbi gb acc num :
NM_013314.3
ncbi mol weight :
44,451 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway 576249!!B Cell Receptor Signaling Pathway 198909!!B Cell Receptor Signaling Pathway 83081!!B Cell Receptor Signaling Pathway 492!!BCR Signaling Pathway 138058!!Cytokine Signaling In Immune System Pathway 366171!!Immune System Pathway 106386!!Interleukin-3, 5 And GM-CSF Signaling Pathway 187094!!NF-kappa B Signaling Pathway 634527
ncbi summary :
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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