Goat anti-BAF53A and BAF53B Antibody | MyBioSource MBS420286 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-BAF53A and BAF53B Antibody

catalog :

MBS420286

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420286

products type :

Antibody

products full name :

Goat anti-BAF53A and BAF53B Antibody

products short name :

BAF53A and BAF53B

products name syn :

BAF53A; BAF53B; ACTL6; BAF53a; BAF53b; actin-like 6A; actin-like 6B; hArpN alpha; actin-related protein; ACTL6A; ACTL6B; 53 kDa BRG1-associated factor B; ARPN-BETA; Arp4; INO80K; MGC5382; BAF complex 53 kDa subunit; BAF53; BRG1-associated factor; INO80 complex subunit K; actin-related protein 4; hArpN beta; BAF53A; BAF53B; ACTL6; BAF53a; BAF53b; actin-like 6A; actin-like 6B; hArpN alpha; actin-related protein; 53 kDa BRG1-associated factor B; ARPN-BETA; MGC5382 Arp4; INO80K; BAF complex 53 kDa subunit; BAF53; BRG1-associated factor; INO80 complex subunit K; actin-related protein 4; hArpN beta

other names :

actin-like protein 6A isoform 1; Actin-like protein 6A; actin-like protein 6A; BAF53; arpNbeta; hArpN beta; INO80 complex subunit K; actin-related protein 4; BAF complex 53 kDa subunit; BRG1-associated factor 53A; actin-related protein Baf53a; 53 kDa BRG1-associated factor A; actin-like 6A; 53 kDa BRG1-associated factor A; Actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; BAF53A; INO80 complex subunit K

products gene name :

ACTL6A/ACTL6B

other gene names :

ACTL6A; ACTL6A; Arp4; ACTL6; BAF53A; INO80K; ARPN-BETA; BAF53; BAF53A; INO80K; BAF53A

uniprot entry name :

ACL6A_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human, Mouse, Rat, Dog, Pig, Cow,

sequence length :

429

sequence :

YEEGGKQCVERKCP

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Western Blot: Approx 48kDa band observed in Hela lysates (predicted MW of 49kDa according to NP_057272, NP_004292). Recommended for use at 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.

other info1 :

Epitope: C Terminus. Immunogen: Peptide with sequence YEEGGKQCVERKCP, from the C Terminus of the protein sequence according to NP_004292.1; NP_817126.1; NP_057272.1. Corresponding Immunizing Peptide: Catalog #MBS425661

other info2 :

Important Note: This antibody is expected to recognise both BAF53A and BAF53B, which are almost identical. Reported variants represent identical protein (NP_817126.1; NP_829888.1).

ncbi gi num :

4757718

ncbi acc num :

NP_004292.1

ncbi gb acc num :

NM_004301.3

ncbi mol weight :

43,236 Da

ncbi pathways :

C-MYC Pathway 169344!!Chromatin Modifying Enzymes Pathway 941403!!Chromatin Organization Pathway 941402!!Gastric Cancer Network 1 Pathway 760635!!HATs Acetylate Histones Pathway 941404!!Prostate Cancer Pathway 755440!!RMTs Methylate Histone Arginines Pathway 1016172!!TNF-alpha/NF-kB Signaling Pathway 198884!!Validated Targets Of C-MYC Transcriptional Activation Pathway 169351

ncbi summary :

This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008]

size :

0.1 mg

price :

290 USD

more info or order :

MyBioSource product webpage