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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-STELLAR Antibody
catalog :
MBS420284
quantity :
0.1 mg
price :
225 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420284
products type :
Antibody
products full name :
Goat anti-STELLAR Antibody
products short name :
STELLAR
products name syn :
STELLAR; germ and embryonic stem cell enriched protein STELLA; developmental pluripotency associated 3 pseudogene, stella-like; STELLA; STELLAR antibody; germ and embryonic stem cell enriched protein STELLA antibody; developmental pluripotency associated 3 pseudogene; stella-like antibody; STELLA antibody
other names :
developmental pluripotency-associated protein 3; Developmental pluripotency-associated protein 3; developmental pluripotency-associated protein 3; developmental pluripotency associated 3; Stella-related protein
products gene name :
STELLAR
other gene names :
DPPA3; DPPA3; STELLA; STELLAR
uniprot entry name :
DPPA3_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Expected from sequence similarity: Human
sequence length :
159
sequence :
NKEPKGVKKESRP
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 64000. Western Blot: Preliminary experiments gave an approx 26kDa band in human ovary and placenta lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 17.9kDa according to NP_954980.1. The 26kDa band was successfully blocked by incubation with the immunizing peptide.
other info1 :
Immunogen: Peptide with sequence C-NKEPKGVKKESRP, from the internal region of the protein sequence according to NP_954980.1. Epitope: Internal region
ncbi gi num :
40548326
ncbi acc num :
NP_954980.1
ncbi gb acc num :
NM_199286.3
ncbi mol weight :
17,851 Da
ncbi summary :
This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X. [provided by RefSeq, Jul 2008]
uniprot summary :
DPPA3: Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis. Chromosomal Location of Human Ortholog: 12p13.31. Cellular Component: cytoplasm; female pronucleus; male pronucleus; nucleus. Molecular Function: methylated histone residue binding. Biological Process: chromatin modification; embryonic cleavage
size1 :
0.1 mg
price1 :
225 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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