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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-ICAM5 precursor Antibody
catalog :
MBS420276
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, cow
application :
immunohistochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420276
products type :
Antibody
products full name :
Goat anti-ICAM5 precursor Antibody
products short name :
ICAM5 precursor
products name syn :
ICAM5; intercellular adhesion molecule 5, telencephalin; TLCN; TLN; intercellular adhesion molecule 5; telencephalin; ICAM5 antibody; intercellular adhesion molecule 5; telencephalin antibody; TLCN antibody; TLN antibody; intercellular adhesion molecule 5 antibody; telencephalin antibody; ICAM5 precursor
other names :
intercellular adhesion molecule 5; Intercellular adhesion molecule 5; intercellular adhesion molecule 5; intercellular adhesion molecule 5; Telencephalin
products gene name :
ICAM5
other gene names :
ICAM5; ICAM5; TLN; TLCN; TLCN; TLN; ICAM-5
uniprot entry name :
ICAM5_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Pig, Cow
sequence length :
924
sequence :
ESPAEGEVFAIQ
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 128000. Immunohistochemistry: In paraffin embedded Human Brain (Cerebral Cortex) shows axon/dendrite staining leaving cell bodies relatively unstained. Recommended concentration, 2-4ug/ml. Western Blot: Preliminary experiments gave an approx 200-250kDa band in lysates of Human Brain (Frontal Cortex and Hippocampus) and Mouse Brain after 0. 05 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 97.2kDa according to NP_003250.2. The 200-250kDa band was successfully blocked by incubation with the immunizing peptide.
other info1 :
Immunogen: Peptide with sequence C-ESPAEGEVFAIQ, from the C Terminus of the protein sequence according to NP_003250.3. Epitope: C Terminus
ncbi gi num :
189571583
ncbi acc num :
NP_003250.3
ncbi gb acc num :
NM_003259.3
ncbi mol weight :
97,116 Da
ncbi pathways :
Adaptive Immune System Pathway (1269171); Extracellular Matrix Organization Pathway (1270244); Immune System Pathway (1269170); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (1269201); Integrin Cell Surface Interactions Pathway (1270260)
ncbi summary :
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008]
uniprot summary :
ICAM5: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). Belongs to the immunoglobulin superfamily. ICAM family. Protein type: Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: integrin binding; protein binding. Biological Process: cell adhesion; cell-cell adhesion; extracellular matrix organization and biogenesis; phagocytosis; regulation of immune response
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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