catalog number :
MBS420274
products full name :
Goat anti-ADRB2R / ADRB2 Antibody
products short name :
ADRB2R/ADRB2
products name syn :
ADRB2; ADRB2R; adrenergic; beta-2-; receptor; surface [Homo sapiens]; HGNC:286; ADRBR; B2AR; BAR; BETA2AR; beta-2 adrenergic receptor; beta-2 adrenoceptor; catecholamine receptor; ADRB2R; adrenergic, beta-2-, receptor, surface; HGNC:286; ADRBR; B2AR; BAR; BETA2AR; beta-2 adrenergic receptor; beta-2 adrenoceptor; catecholamine receptor
other names :
beta-2 adrenergic receptor; Beta-2 adrenergic receptor; beta-2 adrenergic receptor; beta-2 adrenoceptor; beta-2 adrenoreceptor; catecholamine receptor; adrenoceptor beta 2 surface; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2, surface; Beta-2 adrenoreceptor; Beta-2 adrenoceptor
products gene name :
ADRB2
other gene names :
ADRB2; ADRB2; BAR; B2AR; ADRBR; ADRB2R; BETA2AR; ADRB2R; B2AR; Beta-2 adrenoceptor
uniprot entry name :
ADRB2_HUMAN
reactivity :
Human, Dog, Cow,
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 48kDa band observed in human liver lysates (calculated MW of 46.6kDa according to NP_000015.1). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-HQGTVPSDNIDSQ, from the C Terminus of the protein sequence according to NP_000015.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426413
ncbi acc num :
NP_000015.1
ncbi gb acc num :
NM_000024.5
ncbi mol weight :
46,459 Da
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway 908257!!Adrenergic Signaling In Cardiomyocytes Pathway 909696!!Adrenoceptors Pathway 106365!!Amine Ligand-binding Receptors Pathway 106363!!Arf6 Signaling Events Pathway 138034!!Arf6 Trafficking Events Pathway 137954!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357
ncbi summary :
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]