catalog number :
MBS420266
products full name :
Goat anti-Biglycan Preproprotein Antibody
products short name :
Biglycan Preproprotein
products name syn :
Biglycan Preproprotein; biglycan; BGN; DSPG1; PG-S1; PGI; SLRR1A; bone/cartilage proteoglycan-I; dermatan sulphate proteoglycan I; small leucine-rich protein 1A; Biglycan Preproprotein; biglycan; BGN; DSPG1; PG-S1; PGI; SLRR1A; bone/cartilage proteoglycan-I; dermatan sulphate proteoglycan I; small leucine-rich protein 1A
other names :
biglycan preproprotein; Biglycan; biglycan; biglycan proteoglycan; bone/cartilage proteoglycan I; bone/cartilage proteoglycan-I; small leucine-rich protein 1A; dermatan sulphate proteoglycan I; biglycan; Bone/cartilage proteoglycan I; PG-S1
other gene names :
BGN; BGN; PGI; DSPG1; PG-S1; SLRR1A; SLRR1A
uniprot entry name :
PGS1_HUMAN
reactivity :
Human, Mouse, Rat, Dog
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: IHC has been successfully applied on Human Achilles tendons (PMID: 23001016). Western Blot: Approx 37kDa band observed in Rat Skin lysates (calculated MW of 41.7kDa according to Human NP_001702.1 and Rat NP_058783.1). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-DRLAIQFGNYKK, from the C Terminus of the protein sequence according to NP_001702.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426898
ncbi acc num :
NP_001702.1
ncbi gb acc num :
NM_001711.4
ncbi mol weight :
41,654 Da
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway 645305!!CS/DS Degradation Pathway 645311!!Chondroitin Sulfate Biosynthesis Pathway 645309!!Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway 645308!!Dermatan Sulfate Biosynthesis Pathway 645310!!Disease Pathway 530764!!ECM Proteoglycans Pathway 833812!!Extracellular Matrix Organization Pathway 576262!!Glycogen Storage Diseases Pathway 980468!!Glycosaminoglycan Metabolism Pathway 645297
ncbi summary :
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex. [provided by RefSeq, Nov 2009]