catalog number :
MBS420258
products full name :
Goat anti-AP-2 gamma Antibody
products short name :
AP-2 gamma
products name syn :
TFAP2C; ERF1; TFAP2G; hAP-2g; AP2-GAMMA; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); estrogen receptor factor 1; transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma); TFAP2C; ERF1; TFAP2G; hAP-2g; AP2-GAMMA; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); estrogen receptor factor 1; transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma)
other names :
transcription factor AP-2 gamma; Transcription factor AP-2 gamma; transcription factor AP-2 gamma; estrogen receptor factor 1; transcription factor ERF-1; activating enhancer-binding protein 2 gamma; transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma); transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); Activating enhancer-binding protein 2 gamma; Transcription factor ERF-1
products gene name :
TFAP2C
other gene names :
TFAP2C; TFAP2C; ERF1; TFAP2G; hAP-2g; AP2-GAMMA; AP2-gamma
uniprot entry name :
AP2C_HUMAN
reactivity :
Human, Rat, Mouse, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Human Skin shows nuclear staining of keratinocytes. Recommended concentration, 2-3ug/ml. Western Blot: WB experiments gave bands at approx 75kDa and 22kDa in Human Placenta and Ovary lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 49.2kDa according to NP_003213.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-NKTLEKMEKHRK, from the C Terminus of the protein sequence according to NP_003213.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425167
ncbi acc num :
NP_003213.1
ncbi gb acc num :
NM_003222.3
ncbi mol weight :
31,010 Da
ncbi summary :
The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. [provided by RefSeq, Jul 2008]