This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-Wiskott-Aldrich Syndrome / WASP Antibody
catalog :
MBS420239
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, enzyme immunoassay
product information
catalog number :
MBS420239
products type :
Antibody
products full name :
Goat anti-Wiskott-Aldrich Syndrome / WASP Antibody
products short name :
Wiskott-Aldrich Syndrome/WASP
products name syn :
WASP; Wiskott-Aldrich syndrome (eczema-thrombocytopenia); WAS; THC; IMD2; thrombocytopenia 1 (X-linked); Wiskott-Aldrich syndrome (eczema-thrombocytopenia) protein; THC1; Wiskott-Aldrich syndrome protein; WAS; WASP; Wiskott-Aldrich syndrome (eczema-thrombocytopenia); THC; IMD2; thrombocytopenia 1 (X-linked); Wiskott-Aldrich syndrome (eczema-thrombocytopenia) protein; THC1; Wiskott-Aldrich syndrome protein
other names :
wiskott-Aldrich syndrome protein; Wiskott-Aldrich syndrome protein; wiskott-Aldrich syndrome protein; eczema-thrombocytopenia; thrombocytopenia 1 (X-linked); Wiskott-Aldrich syndrome
products gene name :
WAS
other gene names :
WAS; WAS; THC; IMD2; SCNX; THC1; WASP; IMD2; WASp
uniprot entry name :
WASP_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog
sequence length :
502
sequence :
SPADKKRSGKKKI
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 60kDa band observed in Human lysates of Tcell line MOLT4 and monocytic cell line U937 (calculated MW of 52.9kDa according to NP_000368.1). Recommended concentration: 0.03-0.1ug/ml. Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-SPADKKRSGKKKI, from the internal region of the protein sequence according to NP_000368.1. Corresponding Immunizing Peptide: Catalog #MBS426192
other info2 :
Important Note: No cross-reactivity expected with N WASP (WASL).
ncbi gi num :
4507909
ncbi acc num :
NP_000368.1
ncbi gb acc num :
NM_000377.2
ncbi mol weight :
52,913 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!B Cell Receptor Signaling Pathway 198909!!Bacterial Invasion Of Epithelial Cells Pathway 149807!!Bacterial Invasion Of Epithelial Cells Pathway 148661!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Fc Gamma R-mediated Phagocytosis Pathway 114228!!Fc Gamma R-mediated Phagocytosis Pathway 106590
ncbi summary :
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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