catalog number :
MBS420222
products full name :
Goat anti-ATGL / Desnutrin Antibody
products short name :
ATGL/Desnutrin
products name syn :
ATGL; DESNUTRIN; PNPLA2; patatin-like phospholipase domain containing 2; 1110001C14Rik; DKFZp667M109; FP17548; PEDF-R; TTS-2.2; TTS2; adipose triglyceride lipase; pigment epithelium-derived factor; transport-secretion protein 2.2; triglyceride hydrolase; Goat Anti-PNPLA2 / Desnutrin; ATGL; DESNUTRIN; PNPLA2; patatin-like phospholipase domain containing 2; 1110001C14Rik; DKFZp667M109; FP17548; PEDF-R; TTS-2.2; TTS2;
adipose triglyceride lipase; pigment epithelium-derived factor; transport-secretion protein 2.2; triglyceride hydrolase
other names :
patatin-like phospholipase domain-containing protein 2; Patatin-like phospholipase domain-containing protein 2; patatin-like phospholipase domain-containing protein 2; TTS2.2; desnutrin; IPLA2-zeta; triglyceride hydrolase; adipose triglyceride lipase; transport-secretion protein 2.2; pigment epithelium-derived factor; calcium-independent phospholipase A2; patatin-like phospholipase domain containing protein 2; patatin-like phospholipase domain containing 2; Adipose triglyceride lipase; Calcium-independent phospholipase A2; Desnutrin; IPLA2-zeta; Pigment epithelium-derived factor; TTS2.2; Transport-secretion protein 2; TTS2
products gene name :
PNPLA2
other gene names :
PNPLA2; PNPLA2; ATGL; TTS2; PEDF-R; FP17548; TTS-2.2; iPLA2zeta; 1110001C14Rik; ATGL; TTS2
uniprot entry name :
PLPL2_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Heart shows intense staining of distinct spots in the myocardial fibres in transverse section. Recommended concentration, 2-3ug/ml. Western Blot: Approx 60kDa band observed in Human Adipose, Heart and Testis lysates (calculated MW of 55.3kDa according to NP_065109.1). Recommended concentration: 0.5-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-NIIEVSKEARKR, from the internal region of the protein sequence according to NP_065109.1. Corresponding Immunizing Peptide: Catalog #MBS428432
other info2 :
Important Note: Pease note this antibody was designed using the Mouse sequence NP_080078.1, which differs by 2 amino acids from the Human sequence NP_065109.1.
ncbi acc num :
NP_065109.1
ncbi gb acc num :
NM_020376.3
ncbi mol weight :
19,875 Da
ncbi pathways :
Acyl Chain Remodeling Of DAG And TAG Pathway 645315!!Acylglycerol Degradation Pathway 413388!!Acylglycerol Degradation Pathway 468272!!Fatty Acid Beta Oxidation Pathway 198865!!Glycerolipid Metabolism Pathway 82986!!Glycerolipid Metabolism Pathway 361!!Glycerophospholipid Biosynthesis Pathway 645313!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976
ncbi summary :
This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy. [provided by RefSeq, Jul 2010]