catalog number :
MBS420194
products full name :
Goat anti-MEPI / SERPINI2 Antibody
products short name :
MEPI/SERPINI2
products name syn :
SERPINI2; MEPI; PI14; PANCPIN; TSA2004; SERPIN12; serine (or cysteine) proteinase inhibitor; clade I (neuroserpin); member 2; serpin peptidase inhibitor; clade I (pancpin); member 2; myoepithelium-derived serine protease inhibitor; protease inhibitor 14; serine (or cysteine) proteinase inhibitor; clade I (pancpin); member 2; SERPINI2; MEPI; PI14; PANCPIN; TSA2004; SERPIN12; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2; serpin peptidase inhibitor, clade I (pancpin), member 2; myoepithelium-derived serine protease inhibitor; protease inhibitor 14; serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2
other names :
serpin I2 isoform 2; Serpin I2; serpin I2; protease inhibitor 14; peptidase inhibitor 14; pancreas-specific protein TSA2004; myoepithelium-derived serine protease inhibitor; serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2; serpin peptidase inhibitor, clade I (pancpin), member 2; Myoepithelium-derived serine protease inhibitor; Pancpin; Pancreas-specific protein TSA2004; Peptidase inhibitor 14; PI-14
products gene name :
SERPINI2
other gene names :
SERPINI2; SERPINI2; MEPI; PI14; PANCPIN; TSA2004; MEPI; PI14; PI-14
uniprot entry name :
SPI2_HUMAN
reactivity :
Human, Mouse, Rat, Dog
sequence :
KGDWKQKFRKEDTQ
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Pancreas, shows cytoplasmic staining of acinar cels and of rare cells in the islets of Langerhans. Recommended concentration, 3ug/ml. Western Blot: Approx 40kDa band observed in Human Pancreas lysates (calculated MW of 46.1kDa according to NP_006208.1 and 47.4kDa according to NP_001012303.1). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-KGDWKQKFRKEDTQ, from the internal region of the protein sequence according to NP_006208.1; NP_001012303.1. Corresponding Immunizing Peptide: Catalog #MBS426775
other info2 :
Important Note: This antibody is expected to recognise both reported isoforms (NP_006208.1; NP_001012303.1).
ncbi acc num :
NP_006208.1
ncbi gb acc num :
NM_006217.4
ncbi mol weight :
46,145 Da
ncbi summary :
The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]