catalog number :
MBS420183
products full name :
Goat anti-BIF-1 / SH3GLB1 Antibody
products short name :
BIF-1/SH3GLB1
products name syn :
SH3GLB1; Bif-1; SH3-domain GRB2-like endophilin B1; CGI-61; KIAA0491; endophilin B1; Bax-interacting factor 1; SH3-containing protein SH3GLB1; SH3-domain; GRB2-like; endophilin B1; SH3-containing protein SH3GLB1 CGI-61 protein endophilin B1; dJ612B15.2; SH3GLB1; Bif-1; SH3-domain GRB2-like endophilin B1; CGI-61; KIAA0491; endophilin B1; Bax-interacting factor 1; SH3-containing protein SH3GLB1; SH3-domain, GRB2-like, endophilin B1; SH3-containing protein SH3GLB1 CGI-61 protein endophilin B1; dJ612B15.2
other names :
endophilin-B1 isoform 1; Endophilin-B1; endophilin-B1; Bax-interacting factor 1; SH3-containing protein SH3GLB1; SH3 domain-containing GRB2-like protein B1; protein phosphatase 1, regulatory subunit 70; SH3-domain GRB2-like endophilin B1; Bax-interacting factor 1; Bif-1; SH3 domain-containing GRB2-like protein B1
products gene name :
SH3GLB1
other gene names :
SH3GLB1; SH3GLB1; Bif-1; CGI-61; PPP1R70; dJ612B15.2; KIAA0491; Bif-1
uniprot entry name :
SHLB1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence :
QKGKVPITYLELLN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 38kDa band observed in lysates of Human T cell line Jurkat and in Human Lung and Placenta (calculated MW of 40.8kDa according to NP_057093.1). Recommended concentration: 0.3-1.0 ug/ml. A minor band of unknown identity was also consistently observed at 50kDa in Jurkat and Placenta. This band was successfully blocked by incubation with the immunising peptide. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-QKGKVPITYLELLN, from the C Terminus of the protein sequence according to NP_057093.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425162
ncbi acc num :
NP_057093.1
ncbi gb acc num :
NM_016009.4
ncbi mol weight :
29,318 Da
ncbi pathways :
Endocytosis Pathway 102279!!Endocytosis Pathway 102181!!Senescence And Autophagy Pathway 198780
ncbi summary :
This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]