catalog number :
MBS420180
products full name :
Goat anti-SLC24A5 Antibody
products short name :
SLC24A5
products name syn :
SLC24A5; solute carrier family 24; member 5; JSX; NCKX5; ion transporter JSX; solute carrier family 24 (sodium/potassium/calcium exchanger); member 5; SLC24A5; solute carrier family 24,member 5; JSX; NCKX5; ion transporter JSX; solute carrier family 24 (sodium/potassium/calcium exchanger),member 5
other names :
sodium/potassium/calcium exchanger 5; Sodium/potassium/calcium exchanger 5; sodium/potassium/calcium exchanger 5; ion transporter JSX; solute carrier family 24, member 5; Na(+)/K(+)/Ca(2+)-exchange protein 5; oculocutaneous albinism 6 (autosomal recessive); solute carrier family 24 (sodium/potassium/calcium exchanger), member 5; Na(+)/K(+)/Ca(2+)-exchange protein 5; Solute carrier family 24 member 5
products gene name :
SLC24A5
other gene names :
SLC24A5; SLC24A5; JSX; OCA6; NCKX5; SHEP4; JSX; NCKX5
uniprot entry name :
NCKX5_HUMAN
reactivity :
Human, Mouse, Rat, Dog
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 40kDa band observed in Mouse Eye and Rat Skin lysates (calculated MW of 54.9 according to Human NP_995322.1, of 55.0kDa according to Mouse NP_778199.2 and of 38.1kDa according to Rat NP_001101239.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Ginger et al, J Biol Chem. 2008 Feb 29;283(9):5486-95; PMID: 18166528). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:2000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence TTPDCRKKFWKN, from the internal region of the protein sequence according to NP_995322.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426349
ncbi acc num :
NP_995322.1
ncbi gb acc num :
NM_205850.2
ncbi mol weight :
48,016 Da
ncbi pathways :
SLC-mediated Transmembrane Transport Pathway 119558!!Sodium/Calcium Exchangers Pathway 119561!!Transmembrane Transport Of Small Molecules Pathway 106572!!Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway 119559
ncbi summary :
This gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation. [provided by RefSeq, Jul 2008]