Goat anti-Bradykinin receptor B1 Antibody | MyBioSource MBS420159 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-Bradykinin receptor B1 Antibody

catalog :

MBS420159

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420159

products type :

Antibody

products full name :

Goat anti-Bradykinin receptor B1 Antibody

products short name :

Bradykinin receptor B1

products name syn :

bradykinin receptor B1; BDKRB1; B1BKR; B1R; BKB1R; BKR1; BRADYB1; BK-1 receptor; bradykinin B1 receptor; bradykinin receptor 1; bradykinin receptor B1 antibody; BDKRB1 antibody; B1BKR antibody; B1R antibody; BKB1R antibody; BKR1 antibody; BRADYB1 antibody; BK-1 receptor antibody; bradykinin B1 receptor antibody; bradykinin receptor 1 antibody; Bradykinin receptor B1; Bradykinin receptor B1

other names :

B1 bradykinin receptor; B1 bradykinin receptor; B1 bradykinin receptor; bradykinin receptor B1

products gene name :

BDKRB1

other gene names :

BDKRB1; BDKRB1; B1R; BKR1; B1BKR; BKB1R; BDKRB2; BRADYB1; BRADYB1; B1R; BK-1 receptor

uniprot entry name :

BKRB1_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human; Expected from sequence similarity: Human

sequence length :

353

sequence :

KVWELYKQCTPK

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 1000. Western Blot: Approx 35kDa band observed in lysates of cell lines Daudi, K562 and U937 calculated MW of 40.5kDa according to NP_000701.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 2-4ug/ml.

other info1 :

Immunogen: Peptide with sequence KVWELYKQCTPK, from the internal region of the protein sequence according to NP_000701.2. Epitope: Internal region

ncbi gi num :

20544172

ncbi acc num :

NP_000701.2

ncbi gb acc num :

NM_000710.3

ncbi mol weight :

40,495 Da

ncbi pathways :

ACE Inhibitor Pathway (198763); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); G Alpha (i) Signalling Events Pathway (1269576); G Alpha (q) Signalling Events Pathway (1269578); GPCR Downstream Signaling Pathway (1269574)

ncbi summary :

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

uniprot summary :

BKR1: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation. Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB1 sub-subfamily. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 14q32.1-q32.2. Cellular Component: endoplasmic reticulum; integral to plasma membrane; neuron projection; plasma membrane. Molecular Function: bradykinin receptor activity; peptide binding; protein binding. Biological Process: cell migration; elevation of cytosolic calcium ion concentration; inflammatory response; negative regulation of blood pressure; negative regulation of cell growth; negative regulation of protein amino acid phosphorylation; positive regulation of leukocyte migration; positive regulation of release of sequestered calcium ion into cytosol; protein kinase C activation; response to lipopolysaccharide; response to mechanical stimulus; sensory perception of pain

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage