catalog number :
MBS420158
products full name :
Goat anti-CKB / Brain Creatine Kinase Antibody
products short name :
CKB/Brain Creatine Kinase
products name syn :
CKB; brain creatine kinase; creatine kinase; brain; B-CK; CKBB; creatine kinase B-chain; creatine kinase-B; CKB; brain creatine kinase; creatine kinase, brain; B-CK; CKBB; creatine kinase B-chain; creatine kinase-B
other names :
creatine kinase B-type; Creatine kinase B-type; creatine kinase B-type; creatine kinase-B; creatine kinase B chain; epididymis luminal protein 211; epididymis secretory protein Li 29; creatine kinase, brain; B-CK; Creatine kinase B chain
other gene names :
CKB; CKB; BCK; B-CK; CKBB; HEL-211; HEL-S-29; CKBB
uniprot entry name :
KCRB_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
sequence :
KPSDEHKTDLNPDN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 45-48kDa band observed in human brain lysates (calculated MW of 42.6kDa according to NP_001814.2). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:2000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-KPSDEHKTDLNPDN, from the internal region of the protein sequence according to NP_001814.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425781
ncbi acc num :
NP_001814.2
ncbi gb acc num :
NM_001823.4
ncbi mol weight :
42,644 Da
ncbi pathways :
Arginine And Proline Metabolism Pathway 82957!!Arginine And Proline Metabolism Pathway 323!!Creatine Metabolism Pathway 106192!!Creatine Pathway 413359!!Creatine Pathway 468234!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Amino Acids And Derivatives Pathway 106169!!Urea Cycle And Metabolism Of Amino Groups Pathway 198758!!Creatine-phosphate Biosynthesis Pathway 545319
ncbi summary :
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]