catalog number :
MBS420151
products full name :
Goat anti-ORP1 Antibody
products short name :
ORP1
products name syn :
OSBPL1A; ORP1; OSBPL1B; FLJ10217; oxysterol binding protein-like 1A; OSBP-related protein 1; oxysterol-binding protein-like 1B; oxysterol-binding protein-related protein 1; ORP-1; oxysterol-binding protein-like 1A; OSBPL1A; ORP1; OSBPL1B; FLJ10217; oxysterol binding protein-like 1A; OSBP-related protein 1; oxysterol-binding protein-like 1B; oxysterol-binding protein-related protein 1; ORP-1; oxysterol-binding protein-like 1A;
other names :
oxysterol-binding protein-related protein 1 isoform 1; Oxysterol-binding protein-related protein 1; oxysterol-binding protein-related protein 1; OSBP-related protein 1; oxysterol binding protein-like 1B; oxysterol-binding protein-related protein 1 variant 1; oxysterol-binding protein-related protein 1 variant 2; oxysterol binding protein-like 1A
products gene name :
OSBPL1A
other gene names :
OSBPL1A; OSBPL1A; ORP1; ORP-1; OSBPL1B; ORP1; OSBP8; OSBPL1; OSBPL1B; ORP-1; OSBP-related protein 1
uniprot entry name :
OSBL1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 48kDa band observed in Human Skeletal Muscle lysates (predicted MW of 50kDa according to NP_060500). Recommended for use at 0.5-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-YWDRNYFNLPDIY, from the C Terminus of the protein sequence according to NP_060500.3; NP_542164.2. Corresponding Immunizing Peptide: Catalog #MBS426109
other info2 :
Important Note: This antibody is expected to recognise both reported human isoforms of this protein.
products references :
Shah AH, Cianciola NL, Mills JL, Sönnichsen FD, Carlin C.; Adenovirus RIDalpha regulates endosome maturation by mimicking GTP-Rab7.; J Cell Biol. 2007 Dec 3; 179(5):965-80.; Pubmed 18039930
ncbi acc num :
NP_060500.3
ncbi gb acc num :
NM_018030.4
ncbi mol weight :
65,095 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Immune System Pathway 106386!!MHC Class II Antigen Presentation Pathway 645290
ncbi summary :
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008]