catalog number : 
MBS420150
products full name : 
Goat anti-MURF1 / TRIM63 (internal) Antibody
products short name : 
MURF1/TRIM63
products name syn : 
TRIM63; tripartite motif-containing 63; HGNC:16007; FLJ32380; IRF; MURF1; MURF2; RNF28; SMRZ; iris ring finger protein; muscle specific ring finger protein 1; muscle specific ring finger protein 2; ring finger protein 28; striated muscle RING zinc finger protein; Goat Anti-MURF1 / TRIM63 (N Term); TRIM63; tripartite motif-containing 63; HGNC:16007; FLJ32380; IRF; MURF1; MURF2; RNF28; SMRZ; iris ring finger protein; muscle specific ring finger protein 1; muscle specific ring finger protein 2; ring finger protein 28; striated muscle RING zinc finger protein
other names : 
E3 ubiquitin-protein ligase TRIM63; E3 ubiquitin-protein ligase TRIM63; E3 ubiquitin-protein ligase TRIM63; ring finger protein 28; iris ring finger protein; muscle specific ring finger protein 2; muscle-specific RING finger protein 1; tripartite motif-containing protein 63; striated muscle RING zinc finger protein; tripartite motif containing 63, E3 ubiquitin protein ligase; Iris RING finger protein; Muscle-specific RING finger protein 1; MuRF-1; MuRF1; RING finger protein 28; Striated muscle RING zinc finger protein; Tripartite motif-containing protein 63
products gene name : 
TRIM63
other gene names : 
TRIM63; TRIM63; IRF; SMRZ; MURF1; MURF2; RNF28; IRF; MURF1; RNF28; SMRZ; MuRF-1; MuRF1
uniprot entry name : 
TRI63_HUMAN
reactivity : 
Human, Mouse, Rat, Dog, Cow
sequence : 
QQYQEQLDKSTKLVE
purity : 
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form : 
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration : 
100ug specific antibody in 200ul
storage stability : 
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application : 
Peptide ELISA (EIA)
app notes : 
Western Blot: Preliminary experiments gave an approx 75kDa band in human heart and skeletal muscle lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 40.2kDa according to NP_115977.2. The 75kDa band was successfully blocked by incubation with the immunizing peptide.  Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 : 
Epitope: Internal Region.  Immunogen: Peptide with sequence C-QQYQEQLDKSTKLVE, from the internal region of the protein sequence according to NP_115977.2.
other info2 : 
Corresponding Immunizing Peptide:  Catalog #MBS426468
ncbi acc num : 
NP_115977.2
ncbi gb acc num : 
NM_032588.3
ncbi mol weight : 
36,950 Da
ncbi pathways : 
Adaptive Immune System Pathway  366160!!Antigen Processing: Ubiquitination   Proteasome Degradation Pathway  366162!!Class I MHC Mediated Antigen Processing   Presentation Pathway  366161!!Immune System Pathway  106386!!TWEAK Signaling Pathway  672452
ncbi summary : 
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]