product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-EP1 receptor/PTGER1 Antibody
catalog :
MBS420141
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420141
products type :
Antibody
products full name :
Goat anti-EP1 receptor/PTGER1 Antibody
products short name :
EP1 receptor/PTGER1
products name syn :
PTGER1; prostaglandin E receptor 1 (subtype EP1), 42kDa; EP1; PGE receptor, EP1 subtype; prostaglandin E receptor 1, subtype EP1; prostanoid EP1 receptor; PTGER1 antibody; prostaglandin E receptor 1 (subtype EP1); 42kDa antibody; EP1 antibody; PGE receptor; EP1 subtype antibody; prostaglandin E receptor 1; subtype EP1 antibody; prostanoid EP1 receptor antibody; EP1 receptor / PTGER1
other names :
prostaglandin E2 receptor EP1 subtype; Prostaglandin E2 receptor EP1 subtype; prostaglandin E2 receptor EP1 subtype; prostaglandin E receptor 1; Prostanoid EP1 receptor
products gene name :
PTGER1
products gene name syn :
EP1
other gene names :
PTGER1; PTGER1; EP1; PGE receptor EP1 subtype; PGE2 receptor EP1 subtype
uniprot entry name :
PE2R1_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human; Expected from sequence similarity: Human
sequence length :
402
sequence :
DSRRRWGAHGPRS
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 128000. Immunohistochemistry: In paraffin embedded Human Kidney shows membranous staining in the epithelial cells of DCT. Recommended concentration, 1-2ug/ml.
other info1 :
Immunogen: Peptide with sequence C-DSRRRWGAHGPRS, from the internal region of the protein sequence according to NP_000946.2. Epitope: Internal region
ncbi gi num :
38505194
ncbi acc num :
NP_000946.2
ncbi gb acc num :
NM_000955.2
ncbi mol weight :
41,801 Da
ncbi pathways :
Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Eicosanoid Ligand-binding Receptors Pathway (1269560); G Alpha (q) Signalling Events Pathway (1269578); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); Gastrin-CREB Signalling Pathway Via PKC And MAPK (1269592); Neuroactive Ligand-receptor Interaction Pathway (83053)
ncbi summary :
The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008]
uniprot summary :
PTGER1: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19p13.1. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: prostaglandin E receptor activity. Biological Process: G-protein coupled receptor protein signaling pathway; response to lipopolysaccharide
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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