antibody

Goat anti-H11 / HSP22 Antibody

MBS420107

0.1 mg

290 USD

polyclonal

goat

nonconjugated

western blot, enzyme immunoassay

Antibody

Goat anti-H11 / HSP22 Antibody

H11/HSP22

HSPB8; heat shock 22kDa protein 8; CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22; Charcot-Marie-Tooth disease; spinal; heat shock 27kDa protein 8; hereditary motor neuropathy; distal; protein kinase H11; small stress protein-like protein HSP22; spinal muscular atrophy; distal; adult; autosomal dominant; E2-induced gene 1; heat shock protein beta-8; HSPB8; heat shock 22kDa protein 8; CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22; Charcot-Marie-Tooth disease, spinal; heat shock 27kDa protein 8; hereditary motor neuropathy, distal; protein kinase H11; small stress protein-like protein HSP22; spinal muscular atrophy, distal, adult, autosomal dominant; E2-induced gene 1; heat shock protein beta-8

heat shock protein beta-8; Heat shock protein beta-8; heat shock protein beta-8; protein kinase H11; alpha-crystallin C chain; E2-induced gene 1 protein; heat shock 27kDa protein 8; small stress protein-like protein HSP22; heat shock 22kDa protein 8; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22

HSPB8

HSPB8; HSPB8; H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22; CRYAC; E2IG1; HSP22; HspB8

HSPB8_HUMAN

Polyclonal

Goat

Human

196

NELPQDSQEVTCT

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Western Blot: Approx 20-25kDa band seen in human skeletal muscle lysate [Predicted MW of approx. 22kDa according to NP_055180]. Recommended for use at 0.5-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.

Epitope: C Terminus. Immunogen: Peptide with sequence NELPQDSQEVTCT, from the C Terminus of the protein sequence according to NP_055180.1.

Corresponding Immunizing Peptide: Catalog #MBS425388

7657146

NP_055180.1

NM_014365.2

21,604 Da

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD