catalog number :
MBS420106
products full name :
Goat anti-Nogo 66 receptor Antibody
products short name :
Nogo 66 receptor
products name syn :
Nogo-66 receptor; RTN4R; reticulon 4 receptor; HGNC:1860; NGR; NOGOR; UNQ330/PRO526; nogo receptor; reticulon 4 receptor precursor; OTTHUMP00000197866; RTN4R; Nogo-66 receptor; reticulon 4 receptor; HGNC:1860; NGR; NOGOR; UNQ330/PRO526; nogo receptor; reticulon 4 receptor precursor; OTTHUMP00000197866
other names :
reticulon-4 receptor; Reticulon-4 receptor; reticulon-4 receptor; UNQ330/PRO526; nogo receptor; Nogo-66 receptor; reticulon 4 receptor; Nogo receptor; NgR; Nogo-66 receptor
products gene name :
RTN4R
other gene names :
RTN4R; RTN4R; NGR; NOGOR; NOGOR; NgR
uniprot entry name :
RTN4R_HUMAN
reactivity :
Human, Mouse, Rat, Pig, Dog
sequence :
LQALPDDTFRDLGN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Experiments gave bands at approx 90-100kDa and 37+40+45kDa in Human brain lysate after 0.3ug/ml antibody staining. These bands were successfully blocked by the immunizing peptide and they correspond to earlier findings in the literature with different antibodies (Wang et al, J Neurosci. 2002 Jul 1;22(13):5505-15). This protein has a calculated MW of 50.7kDa according to NP_075380.1. Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-LQALPDDTFRDLGN, from the internal region of the protein sequence according to NP_075380.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426024
ncbi acc num :
NP_075380.1
ncbi gb acc num :
NM_023004.5
ncbi mol weight :
50,708 Da
ncbi pathways :
Spinal Cord Injury Pathway 739007!!P75(NTR)-mediated Signaling Pathway 138019
ncbi summary :
This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. [provided by RefSeq, Jul 2008]