catalog number :
MBS420099
products full name :
Goat anti-UBE2I Antibody
products short name :
UBE2I
products name syn :
UBE2I; ubiquitin-conjugating enzyme E2I (UBC9 homolog; yeast); C358B7.1; P18; UBC9; SUMO-1-protein ligase; ubiquitin carrier protein; ubiquitin conjugating enzyme 9; ubiquitin-conjugating enzyme E2I; ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9); ubiquitin-conjugating enzyme UbcE2A; ubiquitin-like protein SUMO-1 conjugating enzyme; ubiquitin-protein ligase E2I; OTTHUMP00000198126; OTTHUMP00000198127; UBE2I; ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast); C358B7.1; P18; UBC9; SUMO-1-protein ligase; ubiquitin carrier protein; ubiquitin conjugating enzyme 9; ubiquitin-conjugating enzyme E2I; ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9); ubiquitin-conjugating enzyme UbcE2A; ubiquitin-like protein SUMO-1 conjugating enzyme; ubiquitin-protein ligase E2I; OTTHUMP00000198126; OTTHUMP00000198127
other names :
SUMO-conjugating enzyme UBC9; SUMO-conjugating enzyme UBC9; SUMO-conjugating enzyme UBC9; SUMO-protein ligase; SUMO-1-protein ligase; ubiquitin-protein ligase I; ubiquitin carrier protein 9; ubiquitin carrier protein I; ubiquitin-protein ligase E2I; ubiquitin conjugating enzyme 9; ubiquitin-conjugating enzyme UbcE2A; ubiquitin-like protein SUMO-1 conjugating enzyme; ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast); ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9); ubiquitin-conjugating enzyme E2I; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; Ubiquitin-conjugating enzyme E2 I; Ubiquitin-protein ligase I; p18
products gene name :
UBE2I
other gene names :
UBE2I; UBE2I; P18; UBC9; C358B7.1; UBC9; UBCE9
uniprot entry name :
UBC9_HUMAN
reactivity :
Human, Mouse, Rat, Dog
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
app notes :
Immunohistochemistry: In paraffin embedded Human Kidney, shows nuclear staining of some epithelial cells of glomeruli and renal tubules. Recommended concentration, 1ug/ml. Western Blot: Approx 17kDa band observed in Human Kidney, Lung and Testis lysates and in Mouse and Rat Heart, Spleen and Testis lysates (calculated MW of 18.0kDa according to Human NP_003336.1). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000. Immunocytochemsitry: An anonymous customer found positive results in Mouse oocytes.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence SGIALSRLAQERK-C, from the N Terminus of the protein sequence according to NP_003336.1; NP_919235.1; NP_919236.1; NP_919237.1. Corresponding Immunizing Peptide: Catalog #MBS426845
other info2 :
Important Note: This antibody is expected to recognize all reported isoforms (NP_003336.1, NP_919235.1, NP_919236.1 and NP_919237.1).
ncbi acc num :
NP_003336.1
ncbi gb acc num :
NM_003345.4
ncbi mol weight :
18,007 Da
ncbi pathways :
Androgen Receptor Signaling Pathway 198806!!C-MYB Transcription Factor Network Pathway 138073!!Cell Cycle Pathway 530733!!Coregulation Of Androgen Receptor Activity Pathway 138085!!Meiosis Pathway 477133!!Meiotic Synapsis Pathway 477134!!Metabolism Of Proteins Pathway 106230!!MicroRNAs In Cancer Pathway 852705!!MicroRNAs In Cancer Pathway 852928!!NF-kappa B Signaling Pathway 634527
ncbi summary :
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]