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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-VDAC2 (C Terminus) Antibody
catalog :
MBS420094
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420094
products type :
Antibody
products full name :
Goat anti-VDAC2 (C Terminus) Antibody
products short name :
VDAC2
products name syn :
Goat Anti-VDAC2 (Internal) Antibody; VDAC2; voltage-dependent anion channel 2; RP11-375G3.1; FLJ23841; VDAC2 antibody; voltage-dependent anion channel 2 antibody; RP11-375G3.1 antibody; FLJ23841 antibody; VDAC2 (C Terminus)
other names :
voltage-dependent anion-selective channel protein 2 isoform 2; Voltage-dependent anion-selective channel protein 2; voltage-dependent anion-selective channel protein 2; voltage dependent anion channel 2; Outer mitochondrial membrane protein porin 2
products gene name :
VDAC2
other gene names :
VDAC2; VDAC2; POR; VDAC-2; hVDAC2
uniprot entry name :
VDAC2_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human, Rat; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
sequence length :
294
sequence :
GHKVGLALELEA
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 4000. Western Blot: Approx 30kDa band observed in Human Brain (Cerebellum) and Rat Brain lysates (calculated MW of 31.6kDa according to NP_003366.2). Recommended concentration: 1-3ug/ml.
other info1 :
Immunogen: Peptide with sequence C-GHKVGLALELEA, from the C Terminus of the protein sequence according to NP_003366.2. Epitope: C Terminus
ncbi gi num :
42476281
ncbi acc num :
NP_003366.2
ncbi gb acc num :
NM_003375.4
ncbi mol weight :
30,412 Da
ncbi pathways :
Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512); Parkinson's Disease Pathway (83098); CGMP-PKG Signaling Pathway (983748); CGMP-PKG Signaling Pathway (985584)
ncbi summary :
This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
uniprot summary :
VDAC2: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective. Interacts with hexokinases. Expressed in all tissues examined. Belongs to the eukaryotic mitochondrial porin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Mitochondrial; Channel, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 10q22. Cellular Component: lipid raft; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion; myelin sheath; nucleus; pore complex; synaptic vesicle. Molecular Function: nucleotide binding; porin activity; protein binding; voltage-gated anion channel activity. Biological Process: anion transport; negative regulation of protein polymerization; transmembrane transport
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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