catalog number :
MBS420079
products full name :
Goat anti-G6PD (aa 305 - 318) Antibody
products short name :
G6PD
products name syn :
G6PD; glucose-6-phosphate dehydrogenase; G6PD1; glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate dehydrogenase; G6PD; Goat Anti-G6PD (aa 308 - 320); G6PD; glucose-6-phosphate dehydrogenase; G6PD1; glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate dehydrogenase; G6PD
other names :
glucose-6-phosphate 1-dehydrogenase isoform a; Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate dehydrogenase
products gene name :
G6PD
other gene names :
G6PD; G6PD; G6PD1; G6PD
uniprot entry name :
G6PD_HUMAN
reactivity :
Human, Mouse, Rat, Dog
sequence :
KPASTNSDDVRDEK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 55kDa band observed in Human Peripheral Blood Mononucleocyte lysates (calculated MW of 59.3kDa according to NP_001035810.1). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-KPASTNSDDVRDEK, from the internal region of the protein sequence according to NP_000393.4 ; NP_001035810.1. Corresponding Immunizing Peptide: Catalog #MBS428596
other info2 :
Important Note: This antibody is expected to recognise both reported isoforms (NP_000393.4 and NP_001035810.1).
ncbi acc num :
NP_000393.4
ncbi gb acc num :
NM_000402.4
ncbi mol weight :
62,468 Da
ncbi pathways :
Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Disease Pathway 530764!!Glutathione Metabolism Pathway 82973!!Glutathione Metabolism Pathway 198824!!Glutathione Metabolism Pathway 343!!Glycogen Storage Diseases Pathway 980468!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Carbohydrates Pathway 106196
ncbi summary :
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]