catalog number :
MBS420061
products full name :
Goat anti-AKAP8 / AKAP95 Antibody
products short name :
AKAP8/AKAP95
products name syn :
AKAP8; AKAP95; DKFZp586B1222; A kinase (PRKA) anchor protein 8; A kinase anchor protein 95; A-kinase anchor protein 8; A-kinase anchor protein; 95kDa; AKAP95; DKFZp586B1222; A kinase (PRKA) anchor protein 8; A kinase anchor protein 95; A-kinase anchor protein 8; A-kinase anchor protein, 95kDa
other names :
A-kinase anchor protein 8; A-kinase anchor protein 8; A-kinase anchor protein 8; A-kinase anchor protein, 95kDa; A kinase (PRKA) anchor protein 8; A-kinase anchor protein 95 kDa; AKAP 95
products gene name :
AKAP8
other gene names :
AKAP8; AKAP8; AKAP-8; AKAP95; AKAP 95; AKAP-95; AKAP95; AKAP-8; AKAP 95
uniprot entry name :
AKAP8_HUMAN
reactivity :
Human, Mouse, Rat, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Experiments gave a band at approx 100kDa in Human Liver lysate after 1ug/ml antibody staining. This band corresponds to the 95kDa band reported in literature (PMID: 10601332). This protein has a calculated MW of 76.1kDa according to NP_005849. Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence DQGYGGYGAWSAG-C, from the N Terminus of the protein sequence according to NP_005849.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426517
ncbi acc num :
NP_005849.1
ncbi gb acc num :
NM_005858.3
ncbi mol weight :
76,108 Da
ncbi pathways :
G Protein Signaling Pathways 198849!!TNF-alpha/NF-kB Signaling Pathway 198884
ncbi summary :
This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]