This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-HSD11B1 / HDL Antibody
catalog :
MBS420055
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, cow
application :
western blot, enzyme immunoassay
product information
catalog number :
MBS420055
products type :
Antibody
products full name :
Goat anti-HSD11B1 / HDL Antibody
products short name :
HSD11B1/HDL
products name syn :
HSD11B1; HDL; 11-DH; HSD11L; MGC13539; 11-beta-HSD1; hydroxysteroid (11-beta) dehydrogenase 1; corticosteroid 11-beta-dehydrogenase isozyme 1; HSD11B1; HDL; 11-DH; HSD11L; MGC13539; 11-beta-HSD1; hydroxysteroid (11-beta) dehydrogenase 1; corticosteroid 11-beta-dehydrogenase isozyme 1; HSD11; HSD11B; SDR26C1; 11-beta-hydroxysteroid dehydrogenase 1; OTTHUMP00000034650; short chain dehydrogenase/reductase family 26C, member 1
other names :
corticosteroid 11-beta-dehydrogenase isozyme 1; Corticosteroid 11-beta-dehydrogenase isozyme 1; corticosteroid 11-beta-dehydrogenase isozyme 1; short chain dehydrogenase/reductase family 26C, member 1; hydroxysteroid (11-beta) dehydrogenase 1; 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11-beta-HSD1
products gene name :
HSD11B1
other gene names :
HSD11B1; HSD11B1; HDL; 11-DH; HSD11; HSD11B; HSD11L; CORTRD2; SDR26C1; 11-beta-HSD1; HSD11; HSD11L; 11-DH; 11-beta-HSD1
uniprot entry name :
DHI1_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Cow
sequence length :
292
sequence :
CTSYNMDRFINK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 35kDa band observed in Human Liver lysates (calculated MW of 32.4kDa according to NP_005516.1 and NP_861420.1). Recommended concentration: 0.3-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence CTSYNMDRFINK, from the C Terminus of the protein sequence according to NP_005516.1; NP_861420.1. Corresponding Immunizing Peptide: Catalog #MBS425397
other info2 :
Important Note: This antibody is expected to recognise human HSD11B1 protein. Both NP_005516.1 and NP_861420.1 variants encode the same protein.
ncbi gi num :
5031765
ncbi acc num :
NP_005516.1
ncbi gb acc num :
NM_005525.3
ncbi mol weight :
32,401 Da
ncbi pathways :
C21-Steroid Hormone Biosynthesis, Progesterone = Cortisol/cortisone Pathway 413395!!C21-Steroid Hormone Biosynthesis, Progesterone = Cortisol/cortisone Pathway 468370!!Chemical Carcinogenesis Pathway 673221!!Chemical Carcinogenesis Pathway 673237!!Glucocorticoid Mineralcorticoid Metabolism Pathway 198902!!Glucocorticoid Biosynthesis Pathway 106152!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!Metabolism Of Steroid Hormones And Vitamin D Pathway 106150
ncbi summary :
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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