antibody

Goat anti-FABP2 Antibody

MBS420047

0.1 mg

290 USD

polyclonal

goat

nonconjugated

human, mouse, rat, dog, cow

western blot, immunohistochemistry, enzyme immunoassay

Antibody

Goat anti-FABP2 Antibody

FABP2

FABP2; fatty acid binding protein 2; intestinal; FABPI; I-FABP; MGC133132; Fatty acid-binding protein; intestinal; intestinal fatty acid binding protein 2; FABP2; fatty acid binding protein 2, intestinal; FABPI; I-FABP; MGC133132; Fatty acid-binding protein, intestinal; intestinal fatty acid binding protein 2

fatty acid-binding protein, intestinal; Fatty acid-binding protein, intestinal; fatty acid-binding protein, intestinal; fatty acid-binding protein 2; intestinal-type fatty acid-binding protein; fatty acid binding protein 2, intestinal; Fatty acid-binding protein 2; Intestinal-type fatty acid-binding protein; I-FABP

FABP2

FABP2; FABP2; FABPI; I-FABP; FABPI; I-FABP

FABPI_HUMAN

Polyclonal

Goat

Human, Mouse, Rat, Dog, Pig, Cow

132

EGVEAKRIFKKD

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry: In paraffin embedded Human Small Intestine shows strong staining of basement membrane and weaker staining of enterocytes. Recommended concentration, 2-3ug/ml. Western Blot: A very strong approx 16kDa band observed in Human Duodenum lysates (calculated MW of 15.2kDa according to NP_000125.1). In transfected HEK293 transiently expressing FABP2 a band of approx. 18kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.001ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.

Epitope: C Terminus. Immunogen: Peptide with sequence C-EGVEAKRIFKKD, from the C Terminus of the protein sequence according to NP_000125.2.

Corresponding Immunizing Peptide: Catalog #MBS425354

194097325

NP_000125.2

NM_000134.3

15,207 Da

Fat Digestion And Absorption Pathway 194385!!Fat Digestion And Absorption Pathway 194324!!PPAR Signaling Pathway 83042!!PPAR Signaling Pathway 450

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD