This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-GAB2 Antibody
catalog :
MBS420041
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, enzyme immunoassay
product information
catalog number :
MBS420041
products type :
Antibody
products full name :
Goat anti-GAB2 Antibody
products short name :
GAB2
products name syn :
GAB2; GRB2-associated binding protein 2; KIAA0571; Grb2-associated binder 2; GAB2; GRB2-associated binding protein 2; KIAA0571; Grb2-associated binder 2
other names :
GRB2-associated-binding protein 2 isoform a; GRB2-associated-binding protein 2; GRB2-associated-binding protein 2; pp100; Grb2-associated binder 2; growth factor receptor bound protein 2-associated protein 2; GRB2-associated binding protein 2; GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100
products gene name :
GAB2
other gene names :
GAB2; GAB2; KIAA0571
uniprot entry name :
GAB2_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog
sequence length :
676
sequence :
QVDKEKTQALQN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 80kDa band observed in lysates of cell line K562 (calculated MW of 74.5kDa according to NP_536739.1). Recommended concentration: 0.5-1.5ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: Internal Region (Near the C Terminus). Immunogen: Peptide with sequence C-QVDKEKTQALQN, from the internal region (near the C Terminus) of the protein sequence according to NP_536739.1; NP_036428.1. Corresponding Immunizing Peptide: Catalog #MBS425540
other info2 :
Important Note: This antibody is expected to recognize both reported isoforms (NP_536739.1; NP_036428.1).
ncbi gi num :
18105042
ncbi acc num :
NP_536739.1
ncbi gb acc num :
NM_080491.2
ncbi mol weight :
69,968 Da
ncbi pathways :
B Cell Receptor Signaling Pathway 198909!!Chronic Myeloid Leukemia Pathway 83116!!Chronic Myeloid Leukemia Pathway 528!!Cytokine Signaling In Immune System Pathway 366171!!Disease Pathway 530764!!EGFR1 Signaling Pathway 198782!!Fc Epsilon RI Signaling Pathway 83082!!Fc Epsilon RI Signaling Pathway 493!!Fc Epsilon Receptor (FCERI) Signaling Pathway 833825!!Fc Gamma R-mediated Phagocytosis Pathway 114228
ncbi summary :
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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