Goat anti-MS2/ADAM8/CD156 Antibody | MyBioSource MBS420028 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-MS2/ADAM8/CD156 Antibody

catalog :

MBS420028

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420028

products type :

Antibody

products full name :

Goat anti-MS2/ADAM8/CD156 Antibody

products short name :

MS2/ADAM8/CD156

products name syn :

ADAM8; CD156; a disintegrin and metalloproteinase domain 8; CD156 MS2; ADAM metallopeptidase domain 8; MGC134985; MS2; cell surface antigen MS2; disintegrin and metalloproteinase domain-containing protein 8; human leukocyte differentiation antigen; ADAM8 antibody; CD156 antibody; a disintegrin and metalloproteinase domain 8 antibody; CD156 MS2 antibody; ADAM metallopeptidase domain 8 antibody; MGC134985 antibody; MS2 antibody; cell surface antigen MS2 antibody; disintegrin and metalloproteinase domain-containing protein 8 antibody; human leukocyte differentiation antigen antibody; MS2 / ADAM8 / CD156

other names :

disintegrin and metalloproteinase domain-containing protein 8 isoform 1; Disintegrin and metalloproteinase domain-containing protein 8; disintegrin and metalloproteinase domain-containing protein 8; ADAM metallopeptidase domain 8; Cell surface antigen MS2; CD_antigen: CD156a

products gene name :

ADAM8

products gene name syn :

MS2; CD156

other gene names :

ADAM8; ADAM8; MS2; CD156; CD156a; MS2; ADAM 8

uniprot entry name :

ADAM8_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human; Expected from sequence similarity: Human

sequence length :

824

sequence :

QRKQGAGAPTAP

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Approx 100kDa band observed in Human Bone Marrow and Peripheral Blood Mononucleocytes lysates (calculated MW of 88.8kDa according to NP_001100.3). Recommended concentration: 1-3ug/ml.

other info1 :

Immunogen: Peptide with sequence C-QRKQGAGAPTAP, from the C Terminus of the protein sequence according to NP_001100.3; NP_001157962.1. Epitope: C Terminus

other info2 :

Note: This antibody is expected to recognise isoform 1 and 3 (NP_001100.3; NP_001157962.1).

ncbi gi num :

256773264

ncbi acc num :

NP_001100.3

ncbi gb acc num :

NM_001109.4

ncbi mol weight :

80,262 Da

ncbi pathways :

Degradation Of The Extracellular Matrix Pathway (1270257); Extracellular Matrix Organization Pathway (1270244)

ncbi summary :

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]

uniprot summary :

ADAM8: Possible involvement in extravasation of leukocytes. Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; EC 3.4.24.-; Protease. Chromosomal Location of Human Ortholog: 10q26.3. Cellular Component: cell surface; cytoplasm; dense core granule membrane; integral to plasma membrane; plasma membrane; podosome; specific granule. Molecular Function: calcium ion binding; cell adhesion molecule binding; metalloendopeptidase activity; metallopeptidase activity; protein binding; protein self-association; serine-type endopeptidase activity; zinc ion binding. Biological Process: activation of NF-kappaB transcription factor; angiogenesis; cell morphogenesis; cell-cell adhesion; extracellular matrix disassembly; inflammatory response; leukocyte migration during inflammatory response; lymphocyte chemotaxis; negative regulation of neuron apoptosis; positive regulation of acute inflammatory response; positive regulation of bone resorption; positive regulation of cell adhesion; positive regulation of membrane protein ectodomain proteolysis; positive regulation of protein kinase B signaling cascade; positive regulation of protein secretion; positive regulation of T cell differentiation in the thymus; proteolysis; regulation of cell-cell adhesion

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage