product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-ADRA2A Antibody
catalog :
MBS420023
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS420023
products type :
Antibody
products full name :
Goat anti-ADRA2A Antibody
products short name :
ADRA2A
products name syn :
ADRA2A; adrenergic; alpha-2A-; receptor; ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32; OTTHUMP00000058849; alpha-2A-adrenergic receptor; alpha-2AAR subtype C10; adrenergic, alpha-2A-, receptor; ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32; OTTHUMP00000058849; alpha-2A-adrenergic receptor; alpha-2AAR subtype C10
other names :
alpha-2A-adrenergic receptor; Alpha-2A adrenergic receptor; alpha-2A adrenergic receptor; alpha-2A adrenoceptor; alpha-2AAR subtype C10; alpha-2A adrenoreceptor; adrenergic, alpha-2A-, receptor; alpha-2 adrenergic receptor subtype C10; alpha-2-adrenergic receptor, platelet type; adrenoceptor alpha 2A; Alpha-2 adrenergic receptor subtype C10; Alpha-2A adrenoreceptor; Alpha-2A adrenoceptor; Alpha-2AAR
products gene name :
ADRA2A
other gene names :
ADRA2A; ADRA2A; ADRA2; ADRAR; ZNF32; ADRA2R; ALPHA2AAR; ADRA2R; ADRAR; Alpha-2A adrenoceptor; Alpha-2AAR
uniprot entry name :
ADA2A_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog
sequence length :
450
sequence :
TERRPNGLGPERS
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB)
app notes :
Western Blot: Preliminary experiments gave a band at approx 37kDa and a minor band at approx 23kDa in Human Brain lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 49.0kDa according to NP_000672.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). Peptide ELISA: antibody detection limit dilution 1:32000. Immunofluorescence: This product has been successfully used in IF on Mouse primary DRG cultured neurons.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-TERRPNGLGPERS, from the internal region of the protein sequence according to NP_000672.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425446
ncbi gi num :
15718670
ncbi acc num :
NP_000672.2
ncbi gb acc num :
NM_000681.2
ncbi mol weight :
48,957 Da
ncbi pathways :
Adrenaline Signalling Through Alpha-2 Adrenergic Receptor Pathway 119542!!Adrenaline,noradrenaline Inhibits Insulin Secretion Pathway 105923!!Adrenoceptors Pathway 106365!!Amine Ligand-binding Receptors Pathway 106363!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!G Alpha (i) Signalling Events Pathway 119550!!G Alpha (z) Signalling Events Pathway 119551!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886
ncbi summary :
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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