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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-ALS2CR2 / ILPIP Antibody
catalog :
MBS420020
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, dog, cow
application :
western blot, immunohistochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420020
products type :
Antibody
products full name :
Goat anti-ALS2CR2 / ILPIP Antibody
products short name :
ALS2CR2/ILPIP
products name syn :
STRADB; ALS2CR2; ILPIP; PAPK; ILPIPA; CALS-21; PRO1038; amyotrophic lateral sclerosis 2 (juvenile) chromosome region; candidate 2; ILP-interacting protein ILPIPA; STE20-related kinase adaptor beta; STRAD beta; pseudokinase ALS2CR2; STRADB; ALS2CR2; ILPIP; PAPK; ILPIPA; CALS-21; PRO1038; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2; ILP-interacting protein ILPIPA; STE20-related kinase adaptor beta; STRAD beta; pseudokinase ALS2CR2
other names :
STE20-related kinase adapter protein beta isoform 1; STE20-related kinase adapter protein beta; STE20-related kinase adapter protein beta; STRAD beta; pseudokinase ALS2CR2; ILP-interacting protein ILPIPA; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; STE20-related kinase adaptor beta; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; CALS-21; ILP-interacting protein; Pseudokinase ALS2CR2
products gene name :
STRADB
other gene names :
STRADB; STRADB; PAPK; ILPIP; ILPIPA; ALS2CR2; CALS-21; PRO1038; ALS2CR2; ILPIP; STRAD beta
uniprot entry name :
STRAB_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Dog, Cow
sequence length :
418
sequence :
CDFPDEKDSYWEF
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: Immunohistochemistry: In paraffin embedded Human Heart shows staining of myocardial fibres in transverse section. Recommended concentration, 3-5ug/ml. Western Blot: Approx 35kDa band observed in Human Heart, Liver and Muscle lysates (calculated MW of 47.0kDa according to NP_061041.2 (alpha isoform) and 31.2kDa according to AAF71042.1(beta isoform). In transfected HEK293 transiently expressing ILPIP a band of approx. 48kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence CDFPDEKDSYWEF, from the C Terminus of the protein sequence according to NP_061041.2; AAF71042.1. Corresponding Immunizing Peptide: Catalog #MBS426508
other info2 :
Important Note: This is expected to recognise both human isoforms: ILPIP-alpha (NP_061041.2) and ILPIP-beta (AAF71042.1).
ncbi gi num :
13027388
ncbi acc num :
NP_061041.2
ncbi gb acc num :
NM_018571.5
ncbi mol weight :
31,219 Da
ncbi pathways :
AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Energy Dependent Regulation Of MTOR By LKB1-AMPK Pathway 160972!!IGF1R Signaling Cascade Pathway 730346!!IRS-mediated Signalling Pathway 106426!!IRS-related Events Pathway 106424!!IRS-related Events Triggered By IGF1R Pathway 730348!!Insulin Receptor Signalling Cascade Pathway 106420!!LKB1 Signaling Events Pathway 137957
ncbi summary :
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
size :
0.1 mg
price :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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