catalog number :
MBS420010
products full name :
Goat anti-XAB2/HCNP Antibody
products short name :
XAB2/HCNP
products name syn :
XAB2; HCNP; XPA binding protein 2; HCRN; crn-related protein kim1; DKFZp762C1015; NTC90; SYF1; SYF1 homolog, RNA splicing factor; XAB2 antibody; HCNP antibody; XPA binding protein 2 antibody; HCRN antibody; crn-related protein kim1 antibody; DKFZp762C1015 antibody; NTC90 antibody; SYF1 antibody; SYF1 homolog; RNA splicing factor antibody; XAB2 / HCNP
other names :
pre-mRNA-splicing factor SYF1; Pre-mRNA-splicing factor SYF1; pre-mRNA-splicing factor SYF1; XPA binding protein 2; Protein HCNP; XPA-binding protein 2
products gene name :
XAB2
products gene name syn :
HCNP
other gene names :
XAB2; XAB2; HCNP; HCRN; SYF1; NTC90; HCNP; KIAA1177; SYF1
uniprot entry name :
SYF1_HUMAN
reactivity :
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 8000. Immunohistochemistry: In paraffin embedded Human Brain (Cerebral Cortex) shows nuclear staining. Recommended concentration, 3-4ug/ml. Western Blot: Approx 90kDa band observed in human fibroblast A431 lysates (calculated MW of 100kDa according to NP_064581.2). Recommended concentration: 0.3-1ug/ml.
other info1 :
Immunogen: Peptide with sequence C-SVPAAVFGSLKED, from the C Terminus of the protein sequence according to NP_064581.2. Epitope: C Terminus
ncbi acc num :
NP_064581.2
ncbi gb acc num :
NM_020196.2
ncbi mol weight :
100,010 Da
ncbi pathways :
DNA Repair Pathway (1270350); Dual Incision In TC-NER Pathway (1309119); Formation Of TC-NER Pre-Incision Complex Pathway (1309118); Gap-filling DNA Repair Synthesis And Ligation In TC-NER Pathway (1309120); Nucleotide Excision Repair Pathway (1309111); Spliceosome Pathway (125136); Spliceosome Pathway (124832); Spliceosome, 35S U5-snRNP Pathway (413438); Spliceosome, 35S U5-snRNP Pathway (890602); Transcription-Coupled Nucleotide Excision Repair (TC-NER) Pathway (1309117)
uniprot summary :
XAB2: Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing. Belongs to the crooked-neck family. Protein type: Spliceosome; RNA splicing. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: membrane; nucleoplasm; nucleus. Molecular Function: protein binding. Biological Process: blastocyst development; cerebral cortex development; generation of catalytic spliceosome for first transesterification step; nuclear mRNA splicing, via spliceosome; transcription, DNA-dependent; transcription-coupled nucleotide-excision repair