antibody

Anti-FCRL4 Antibody

MBS417073

0.1 mg

230 USD

polyclonal

rabbit

nonconjugated

western blot, ELISA, immunohistochemistry, enzyme immunoassay

Antibody

Anti-FCRL4 Antibody

[FCRL4]

[Homo sapiens Fc receptor-like 4, mRNA; Fc receptor-like protein 4; Fc receptor-like protein 4; IFGP family protein 2; fc receptor homolog 4; fcR-like protein 4; hIFGP2; immune receptor translocation-associated protein 1; immunoglobulin superfamily Fc receptor, gp42; immunoglobulin superfamily receptor translocation associated 1; Fc receptor-like 4; Fc receptor homolog 4; FcRH4; IFGP family protein 2; hIFGP2; Immune receptor translocation-associated protein 1; CD_antigen: CD307d]

[FCRL4]

[FCRL4; FCRL4; FCRH4; IGFP2; IRTA1; CD307d]

FCRL4_HUMAN

Polyclonal

Rabbit

Human

1830

Affinity purified

Liquid

100ug/100ul

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Testing Data

Testing Data

Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide.

Immunogen: Rabbit polyclonal FCRL4 (1) antibody was raised against a recombinate human FCRL4 protein 22-208aa (BC125173). Antigen Type: Primary Antibody

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]

(1) Falini,B., Agostinelli,C., Bigerna,B., et al.IRTA1 is selectively expressed in nodal and extranodal marginal zone lymphomas. Histopathology 61 (5), 930-941 (2012)

115527760

BC125173

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]

FCRL4: May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response. A chromosomal aberration involving FCRL4 is found in non-Hodgkin lymphoma (NHG). Translocation t(1;1)(p36.3; q21.1-2). A chromosomal aberration involving FCRL4 is found in multiple myeloma (MM). Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: plasma membrane; integral to membrane. Molecular Function: protein binding. Biological Process: immune system process

0.1 mg

230 USD