Anti-cox2 Antibody | MyBioSource MBS416804 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-cox2 Antibody

catalog :

MBS416804

quantity :

0.1 mL

price :

230 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS416804

products type :

Antibody

products full name :

Anti-cox2 Antibody

products short name :

[cox2]

other names :

[Mus musculus prostaglandin-endoperoxide synthase 2 (Ptgs2), mRNA; Prostaglandin G/H synthase 2; prostaglandin G/H synthase 2; PES-2; PGH synthase 2; PHS II; cyclooxygenase 2; cyclooxygenase-2; glucocorticoid-regulated inflammatory cyclooxygenase; gripghs; macrophage activation-associated marker protein P71/73; prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; Cyclooxygenase-2; COX-2; Glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; Macrophage activation-associated marker protein P71/73; PES-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2; TIS10 protein]

products gene name :

[cox2]

other gene names :

[Ptgs2; Ptgs2; COX2; Cox-2; PHS-2; Pghs2; TIS10; PGHS-2]

uniprot entry name :

PGH2_MOUSE

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat. Not yet tested on other species

sequence length :

4150

purity :

Purified

form :

Liquid

concentration :

100ug/100ul

storage stability :

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

tested application :

ELISA, Western Blot (WB)

app notes :

Peptide ELISA titer: 1:10,000-1:40,000. Western blot analysis: 1:200-500. Optimal dilutions/concentrations should be determined by the end user

image1 heading :

Western Blot (WB)

other info1 :

Antibody Type: Primary Antibody. Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide

other info2 :

Immunogen: Synthetic peptide conjugated to KLH

products references :

(1) Yang,H., Zhang,J., Andreasson,K. and Chen,C. COX-2 oxidative metabolism of endocannabinoids augments hippocampal synaptic plasticity. Mol. Cell. Neurosci. 37 (4), 682-695 (2008).

ncbi gi num :

118130137

ncbi acc num :

NP_035328.2

ncbi gb acc num :

NM_011198

ncbi mol weight :

69,013 Da

ncbi pathways :

Arachidonic Acid Metabolism Pathway (83190); Arachidonic Acid Metabolism Pathway (1110914); Arachidonic Acid Metabolism Pathway (366); Arachidonic Acid Metabolism Pathway (522975); Arachidonic Acid Metabolism Via COX (Cyclooxygenase) Pathway (522976); Chemical Carcinogenesis Pathway (673229); Chemical Carcinogenesis Pathway (673237); Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway (1111378); Defective BTD Causes Biotidinase Deficiency Pathway (1111393); Defective CD320 Causes Methylmalonic Aciduria Pathway (1111390)

uniprot summary :

COX-2: Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. Homodimer. Belongs to the prostaglandin G/H synthase family. Protein type: Lipid Metabolism - arachidonic acid; EC 1.14.99.1; Oxidoreductase. Cellular Component: neuron projection; protein complex; membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; caveola; nucleus. Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; prostaglandin-endoperoxide synthase activity; peroxidase activity; protein homodimerization activity; enzyme binding; dioxygenase activity; metal ion binding; heme binding; oxidoreductase activity; lipid binding. Biological Process: positive regulation of nitric oxide biosynthetic process; positive regulation of apoptosis; positive regulation of smooth muscle cell proliferation; positive regulation of NF-kappaB import into nucleus; response to lipopolysaccharide; decidualization; sensory perception of pain; prostaglandin biosynthetic process; fatty acid metabolic process; positive regulation of synaptic transmission, glutamatergic; negative regulation of synaptic transmission, dopaminergic; bone mineralization; negative regulation of cell cycle; negative regulation of cell proliferation; regulation of blood pressure; negative regulation of smooth muscle contraction; positive regulation of cell proliferation; angiogenesis; positive regulation of smooth muscle contraction; inflammatory response; fatty acid biosynthetic process; negative regulation of calcium ion transport; cyclooxygenase pathway; positive regulation of synaptic plasticity; learning; memory; prostaglandin metabolic process; regulation of cell proliferation; ovulation; keratinocyte differentiation; response to cytokine stimulus; brown fat cell differentiation; positive regulation of vasoconstriction; positive regulation of fever; lipid metabolic process; response to oxidative stress; anagen; embryo implantation

size1 :

0.1 mL

price1 :

230 USD

more info or order :

MyBioSource product webpage