Anti-SR-B1 Antibody | MyBioSource MBS416795 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-SR-B1 Antibody

catalog :

MBS416795

quantity :

0.1 mL

price :

230 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS416795

products type :

Antibody

products full name :

Anti-SR-B1 Antibody

products short name :

SR-B1

other names :

scavenger receptor class B member 1 isoform 1; Scavenger receptor class B member 1; scavenger receptor class B member 1; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; scavenger receptor class B type III; scavenger receptor class B, member 1; CD36 and LIMPII analogous 1; CLA-1; CD36 antigen-like 1; Collagen type I receptor, thrombospondin receptor-like 1; SR-BI; CD_antigen: CD36

products gene name :

SR-B1

other gene names :

SCARB1; SCARB1; CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6

uniprot entry name :

SCRB1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Mouse, Rat

sequence length :

509

purity :

Affinity purified

form :

Liquid

concentration :

1ug/1ul

storage stability :

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

tested application :

Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Optimal dilutions to be determined by researchers

other info1 :

Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide. Preservative: Sodium Azide. Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

other info2 :

Immunogen: Peptide

ncbi gi num :

132566684

ncbi acc num :

NP_005496.4

ncbi gb acc num :

NM_005505.4

ncbi mol weight :

56,170 Da

ncbi pathways :

Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Folate Metabolism Pathway (198833); HDL-mediated Lipid Transport Pathway (106158); Hepatitis C Pathway (173973); Hepatitis C Pathway (173907); Lipid Digestion, Mobilization, And Transport Pathway (106111)

ncbi summary :

The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]

uniprot summary :

SCARB1: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester. Belongs to the CD36 family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 12q24.31. Cellular Component: cell surface; integral to plasma membrane; lysosomal membrane; microvillus membrane; plasma membrane; caveola. Molecular Function: apolipoprotein A-I binding; protein binding; protein homodimerization activity; phosphatidylserine binding; lipopolysaccharide binding; transporter activity; low-density lipoprotein binding; apolipoprotein binding; lipopolysaccharide receptor activity; high-density lipoprotein binding; phosphatidylinositol binding. Biological Process: receptor-mediated endocytosis; blood vessel endothelial cell migration; wound healing; viral reproduction; positive regulation of nitric-oxide synthase activity; lipoprotein metabolic process; cholesterol efflux; androgen biosynthetic process; regulation of phagocytosis; recognition of apoptotic cell; lipopolysaccharide transport; cholesterol homeostasis; reverse cholesterol transport; endothelial cell proliferation; detection of lipopolysaccharide; lipopolysaccharide-mediated signaling pathway; adhesion to host; phospholipid transport; cell adhesion; cholesterol catabolic process. Disease: High Density Lipoprotein Cholesterol Level Quantitative Trait Locus 6

size1 :

0.1 mL

price1 :

230 USD

more info or order :

MyBioSource product webpage