catalog number :
MBS416719
products full name :
Anti-Szt2 Antibody
products short name :
[Szt2]
products name syn :
[Anti-SZT2 Antibody]
other names :
[Homo sapiens KIAA0467, mRNA; Protein SZT2; protein SZT2; RP11-506B15.1; seizure threshold 2 protein homolog; seizure threshold 2 homolog (mouse); Seizure threshold 2 protein homolog]
products gene name :
[Szt2]
other gene names :
[SZT2; SZT2; SZT2A; SZT2B; EIEE18; C1orf84; KIAA0467]
uniprot entry name :
SZT2_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity purified
concentration :
100ug/100ul
storage stability :
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:500-1:1,000. Immunohistochemistry: 1:100-1:500. Optimal dilutions/concentrations should be determined by the end user
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC) #2 (IHC)
other info1 :
Antibody Type: Primary Antibody
other info2 :
Immunogen: raised against a recombinate human SZT2 protein 299-479aa (BC052802). Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide
products description :
Lyophilized SZT2 antibody purified by protein affinity column containing 1% BSA and 0.02% NaN3
products references :
(1) Xie,H., Diber,A., Pollock,S. et al. Bridging expressed sequence alignments through targeted cDNA sequencing. Genomics 83 (4), 572-576 (2004)
ncbi mol weight :
20,286 Da
ncbi summary :
The protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. [provided by RefSeq, Jun 2011]
uniprot summary :
SZT2: Involved in oxidative stress. May be involved in superoxide dismutase activity and in neuroprotective effect of peroxisomes, but has no direct dismutase activity when tested in yeast. May enhance epileptogenesis and confer low seizure threshold. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 1p34.2. Cellular Component: peroxisome. Biological Process: central nervous system development; pigmentation; corpus callosum morphogenesis; post-embryonic development. Disease: Epileptic Encephalopathy, Early Infantile, 18