catalog number : 
MBS415910
products full name : 
Anti-CREB1 Antibody
products short name : 
CREB1
other names : 
cyclic AMP-responsive element-binding protein 1 isoform B; Cyclic AMP-responsive element-binding protein 1; cyclic AMP-responsive element-binding protein 1; CREB-1; active transcription factor CREB; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; transactivator protein; cAMP responsive element binding protein 1
products gene name : 
CREB1
other gene names : 
CREB1; CREB1; CREB
uniprot entry name : 
CREB1_HUMAN
reactivity : 
Human, Mouse, Rat. Not yet tested in other species.
purity : 
Affinity purified
concentration : 
100ug/100ul
storage stability : 
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
tested application : 
ELISA (EIA), Immunohistochemistry (IHC)
app notes : 
Peptide ELISA titer: 1:40,000-1:80,000. Immunohistochemistry: 1:50-200. Optimal dilutions/concentrations should be determined by the end user.
other info1 : 
Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide
other info2 : 
Immunogen: Rabbit polyclonal CREB1 antibody was raised against a peptide near intermediate residues of human CREB1 protein.
products description : 
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
products references : 
(1) James,M.A., Lu,Y., Liu,Y., et al.RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway.Cancer Res. 69 (5), 2108-2116 (2009)
ncbi acc num : 
NP_604391.1
ncbi gb acc num : 
NM_134442.3
ncbi mol weight : 
25,445 Da
ncbi pathways : 
AKT Phosphorylates Targets In The Nucleus Pathway  106476!!AMPK Signaling Pathway  989139!!AMPK Signaling Pathway  992181!!ATF-2 Transcription Factor Network Pathway  138006!!ATM Signaling Pathway  920969!!Activated TLR4 Signalling Pathway  106400!!Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway  161033!!Adaptive Immune System Pathway  366160!!Adipogenesis Pathway  198832!!Adrenergic Signaling In Cardiomyocytes Pathway  908257
ncbi summary : 
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]