antibody

Anti-Vimentin Antibody

MBS415887

0.1 mL

230 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, ELISA, immunohistochemistry, enzyme immunoassay

Antibody

Anti-Vimentin Antibody

Vimentin

vimentin; Vimentin; vimentin; epididymis luminal protein 113; vimentin

VIM; VIM; HEL113; CTRCT30

VIME_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat

466

Affinity purified

Liquid

100ug/100ul

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Peptide ELISA titer: 1:40,000-1:80,000. Western blot analysis: 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the end user.

Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide. Antibody Type: Primary antibody

Immunogen: Rabbit polyclonal Vimentin antibody was raised against a peptide at the intermediate residues of human Vimentin protein.

(1)Whipple,R.A., Balzer,E.M., Cho,E.H., et al. Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells. Cancer Res. 68 (14), 5678-5688 (2008)

62414289

NP_003371.2

NM_003380.3

53,652 Da

Alpha6-Beta4 Integrin Signaling Pathway (198807); Apoptosis Pathway (105648); Apoptotic Cleavage Of Cellular Proteins Pathway (105678); Apoptotic Execution Phase Pathway (105677); Aurora B Signaling Pathway (138080); Caspase Cascade In Apoptosis Pathway (137974); Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway (105679); Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115); MicroRNAs In Cancer Pathway (852705)

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009]

Vimentin: an intermediate filament protein. Intermediate filament proteins are expressed in a tissue-specific manner. Desmin is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 10p13. Cellular Component: intermediate filament cytoskeleton; neuron projection; cytoskeleton; focal adhesion; leading edge; cytoplasm; plasma membrane; intermediate filament; peroxisome; cytosol. Molecular Function: protein C-terminus binding; identical protein binding; protein binding; structural constituent of cytoskeleton; double-stranded RNA binding; glycoprotein binding; structural constituent of eye lens. Biological Process: Bergmann glial cell differentiation; viral reproduction; apoptosis; intermediate filament organization; cell motility; astrocyte development; cell structure disassembly during apoptosis; muscle filament sliding. Disease: Cataract 30

0.1 mL

230 USD