antibody

Anti-PGLYRP3 Antibody

MBS415820

0.1 mg

230 USD

polyclonal

rabbit

nonconjugated

western blot, ELISA, enzyme immunoassay

Antibody

Anti-PGLYRP3 Antibody

[PGLYRP3]

[Homo sapiens peptidoglycan recognition protein 3, mRNA; Peptidoglycan recognition protein 3; peptidoglycan recognition protein 3; peptidoglycan recognition protein I alpha; peptidoglycan recognition protein intermediate alpha; peptidoglycan recognition protein 3; Peptidoglycan recognition protein I-alpha; PGLYRPIalpha; PGRP-I-alpha; Peptidoglycan recognition protein intermediate alpha]

[PGLYRP3]

[PGLYRP3; PGLYRP3; PGRPIA; PGRP-Ialpha; PGLYRPIalpha]

PGRP3_HUMAN

Polyclonal

Rabbit

Human

1135

Affinity purified

Liquid

100ug/100ul

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

ELISA (EIA), Western Blot (WB)

ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:1,000-1:2,000. Optimal dilutions/concentrations should be determined by the end user

Western Blot (WB)

Antibody Type: Primary antibody. Buffer: PBS, pH 7.4 with 0.02% Sodium Azide

Immunogen: Raised against a recombinate human PGLYRP3 protein 45-288aa (BC069741).

Rabbit polyclonal PGLYRP3

(1) Davila,S., Froeling,F.E., Tan,A., et al. New genetic associations detected in a host response study to hepatitis B vaccine. Genes Immun. 11 (3), 232-238 (2010).

47479714

BC069741

37,611 Da

This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]

PGLYRP3: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: membrane; extracellular region; intracellular. Molecular Function: peptidoglycan receptor activity; peptidoglycan binding; zinc ion binding; N-acetylmuramoyl-L-alanine amidase activity. Biological Process: defense response to Gram-positive bacterium; negative regulation of natural killer cell differentiation during immune response; detection of bacterium; negative regulation of interferon-gamma production; innate immune response; pattern recognition receptor signaling pathway; peptidoglycan catabolic process

0.1 mg

230 USD