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company name :
MyBioSource
product type :
antibody
product name :
Anti-AMHR2 Antibody
catalog :
MBS415610
quantity :
0.1 mg
price :
230 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS415610
products type :
Antibody
products full name :
Anti-AMHR2 Antibody
products short name :
AMHR2
other names :
Homo sapiens anti-Mullerian hormone receptor, type II, mRNA; Anti-Muellerian hormone type-2 receptor; anti-Muellerian hormone type-2 receptor; AMH type II receptor; MIS type II receptor; Muellerian inhibiting substance type II receptor; Mullerian inhibiting substance type II receptor; anti-Muellerian hormone type II receptor; anti-Mullerian hormone receptor, type II; Anti-Muellerian hormone type II receptor; AMH type II receptor; MIS type II receptor; MISRII; MRII
products gene name :
AMHR2
other gene names :
AMHR2; AMHR2; AMHR; MRII; MISR2; MISRII
uniprot entry name :
AMHR2_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human. Predicted: Mouse, Rat
sequence length :
1829
purity :
Affinity purified
form :
Liquid
concentration :
100ug/100ul
storage stability :
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:1,000-1:2,000. Immunohistochemistry: 1:100-1:500. Optimal dilutions/concentrations should be determined by the end user
other info1 :
Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide
other info2 :
Immunogen: Raised against a recombinate human AMHR2 protein 207-440aa (BC126316)
products description :
Rabbit Polyclonal Antibody
products references :
Hanevik,H.I., Hilmarsen,H.T., Skjelbred,C.F., et al. Single nucleotide polymorphisms in the anti-Mullerian hormone signalling pathway do not determine high or low response to ovarian stimulation. Reprod. Biomed. Online 21 (5), 616-623 (2010)
ncbi gi num :
116497024
ncbi acc num :
BC126316
ncbi mol weight :
51,827 Da
ncbi pathways :
ALK2 Signaling Events Pathway (137983); BMP Signaling Pathway (1084755); BMP Signaling Pathway (1108218); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); TGF-beta Signaling Pathway (83064); TGF-beta Signaling Pathway (475)
ncbi summary :
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009]
uniprot summary :
MISR2: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. Protein type: EC 2.7.11.30; Kinase, protein; Protein kinase, TKL; Membrane protein, integral; Protein kinase, Ser/Thr (receptor); TKL group; STKR family; Type2 subfamily. Chromosomal Location of Human Ortholog: 12q13. Cellular Component: integral to plasma membrane. Molecular Function: protein binding; hormone binding; transforming growth factor beta receptor activity, type II; metal ion binding; receptor activity; ATP binding; receptor signaling protein serine/threonine kinase activity. Biological Process: Mullerian duct regression; transforming growth factor beta receptor signaling pathway; signal transduction; protein amino acid phosphorylation; sex differentiation. Disease: Persistent Mullerian Duct Syndrome, Types I And Ii
size1 :
0.1 mg
price1 :
230 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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