product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-p47Phox Antibody
catalog :
MBS415556
quantity :
0.1 mL
price :
230 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
product information
catalog number :
MBS415556
products type :
Antibody
products full name :
Anti-p47Phox Antibody
products short name :
[p47Phox]
other names :
[Mus musculus neutrophil cytosolic factor 1 (Ncf1), mRNA; Neutrophil cytosol factor 1; neutrophil cytosol factor 1; 47 kDa neutrophil oxidase factor; NADPH oxidase subunit (47 kD); NADPH oxidase subunit (47kDa); neutrophil NADPH oxidase factor 1; neutrophil cytosolic factor 1; 47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; p47-phox]
products gene name :
[p47Phox]
other gene names :
[Ncf1; Ncf1; NOXO2; Ncf-1; NCF-47K; p47phox; p47-phox; p47 phox ]
uniprot entry name :
NCF1_MOUSE
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse, Rat
sequence length :
2721
specificity :
Not yet tested in other species.
purity :
Affinity purified
form :
Liquid
concentration :
100ug/100ul
storage stability :
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Peptide ELISA titer: 1:5,000-1:20,000. Western blot analysis: 1:200-500. Optimal dilutions/concentrations should be determined by the end user.
image1 heading :
Testing Data
other info1 :
Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide. Antibody type: Primary Antibody
other info2 :
Immunogen: Synthetic peptide conjugated to KLH
products references :
(1) Yao,H., Edirisinghe,I., Yang,S.R., et al. Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice. Am. J. Pathol. 172 (5), 1222-1237 (2008)
ncbi gi num :
170172552
ncbi acc num :
NP_035006.3
ncbi gb acc num :
NM_010876
ncbi mol weight :
44,667 Da
ncbi pathways :
Adaptive Immune System Pathway (1110669); Antigen Processing-Cross Presentation Pathway (1110689); Chemokine Signaling Pathway (99271); Chemokine Signaling Pathway (672435); Chemokine Signaling Pathway (96864); Class I MHC Mediated Antigen Processing Presentation Pathway (1110686); Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway (1110690); Disease Pathway (1111319); Fc Gamma R-mediated Phagocytosis Pathway (114297); Fc Gamma R-mediated Phagocytosis Pathway (106590)
uniprot summary :
p47phox: the 47-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils. The holo-oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Contains 2 SH2 domains. Mutations in NCF1, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease. Protein type: Oxidoreductase; EC 1.-.-.-. Cellular Component: Golgi apparatus; extrinsic to membrane; rough endoplasmic reticulum; membrane; cell soma; cytoplasm; dendrite; plasma membrane; cytosol; NADPH oxidase complex. Molecular Function: protein binding; superoxide-generating NADPH oxidase activity; phosphatidylinositol-3,4-bisphosphate binding; lipid binding; SH3 domain binding; phosphoinositide binding. Biological Process: respiratory burst during defense response; respiratory burst; NADP catabolic process; apoptosis; leukocyte mediated cytotoxicity; leukotriene metabolic process; cell proliferation; defense response to Gram-positive bacterium; response to bacterium; negative regulation of smooth muscle contraction; defense response to bacterium; cellular defense response; response to yeast; inflammatory response; protein targeting to membrane; defense response to fungus; superoxide release; hydrogen peroxide biosynthetic process
size1 :
0.1 mL
price1 :
230 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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