product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-FASTK Antibody
catalog :
MBS415492
quantity :
0.1 mL
price :
230 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
immunohistochemistry
more info or order :
product information
catalog number :
MBS415492
products type :
Antibody
products full name :
Anti-FASTK Antibody
products short name :
FASTK
other names :
FASTK protein; Fas-activated serine/threonine kinase; fas-activated serine/threonine kinase; FAST kinase; Fas-activated serine/threonine kinase
products gene name :
FASTK
other gene names :
FASTK; FASTK; FAST
uniprot entry name :
FASTK_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
465
purity :
Affinity purified
form :
Liquid
concentration :
100ug/100ul
storage stability :
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
tested application :
Immunohistochemistry (IHC)
app notes :
Optimal dilutions to be determined by researchers
other info1 :
Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide
other info2 :
Immunogen: Peptide
products description :
This gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]
ncbi gi num :
12653219
ncbi acc num :
AAH00377.1
ncbi mol weight :
58,181 Da
ncbi summary :
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]
uniprot summary :
FASTK: an atypical protein kinase. Fas-mediated apoptosis is characterized by FASTK- dephosphorylation and TIA-1-phosphorylation. Both are activated and FASTK-mediated TIA-1 activation play a key role in apoptosis. Protein type: Protein kinase, atypical; EC 2.7.11.8; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; ATYPICAL group; FAST family. Chromosomal Location of Human Ortholog: 7q35. Cellular Component: mitochondrion. Molecular Function: protein serine/threonine kinase activity; protein binding; Fas-activated serine/threonine kinase activity; ATP binding. Biological Process: regulation of RNA splicing; protein amino acid phosphorylation
size1 :
0.1 mL
price1 :
230 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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