antibody

CD56 PE

MBS396540

100 Tests

280 USD

monoclonal

mouse

PE

[C5.9]

flow cytometry, FACS

Antibody

CD56 PE

[CD56]

[CD56PE; Mouse Single-Color Reagent C5.9; NCAM; Neural Cell Adhesion Molecule]

[neural cell adhesion molecule 1 isoform 1; Neural cell adhesion molecule 1; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; antigen recognized by monoclonal antibody 5.1H11; neural cell adhesion molecule 1]

[CD56]

[NCAM1; NCAM1; CD56; NCAM; MSK39; NCAM; N-CAM-1; NCAM-1]

NCAM1_HUMAN

m

IgG2b

[C5.9]

Mouse

Human

848

Form: RPE. Formulation: Provided as sterile filtered solution in phosphate buffered saline with 0.08% sodium azide and 0.2% carrier protein

Titered for flow cytometry

Product should be stored at 4-8°C. DO NOT FREEZE. Shipping:Room temperature

Flow Cytometry (FC/FACS)

Flow Cytometry (FC/FACS)

Volume: 1 mL

Use: PBMC: Add 10ul of MAB/10 6 PBMC in 100ul PBS. Mix gently and incubate for 15 minutes at 2 degree C to 8 degree C. Wash twice with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. WHOLE BLOOD: Add 10ul of MAB/100ul of whole blood. Mix gently and incubate for 15 minutes at room temperature 20°C. Lyse the whole blood. Wash once with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. See instrument manufacturer's instructions for Lysed Whole Blood and Immunofluorescence analysis with a flow cytometer or microscope. Stability: Reagents are stable for the period shown on the vial label when stored properly.

Single-Color Reagent; Single Color Markers

CD56, M.W. 150,000, is expressed on approximately 10-25% of human peripheral blood lymphocytes. CD56 (NKH-1) is expressed on human peripheral blood natural killer cells, representing a pan NK-cell antigen. Expressed on non-MHC-restricted cytotoxic T cells.

94420689

NP_000606.3

NM_000615.6

P13591

Axon Guidance Pathway (105688); BDNF Signaling Pathway (712093); Cardiac Progenitor Differentiation Pathway (712094); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cytokine Signaling In Immune System Pathway (366171); Developmental Biology Pathway (477129); ECM Proteoglycans Pathway (833812); Extracellular Matrix Organization Pathway (576262); FGF Signaling Pathway (137989)

This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]

Function: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Isoform 3: Cell membrane; Lipid-anchor GPI-anchor. Isoform 4: Cell membrane; Lipid-anchor GPI-anchor . Potential. Isoform 5: Secreted. Isoform 6: Secreted . Potential. Sequence similarities: Contains 2 fibronectin type-III domains.Contains 5 Ig-like C2-type (immunoglobulin-like) domains. Sequence caution: The sequence BAD92680.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

100 Tests

280 USD