product summary
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company name :
MyBioSource
product type :
antibody
product name :
EBNA 3C
catalog :
MBS395758
quantity :
0.25 mg
price :
340 USD
clonality :
polyclonal
host :
sheep
conjugate :
nonconjugated
reactivity :
Epstein-Barr virus
application :
western blot
more info or order :
product information
catalog number :
MBS395758
products type :
Antibody
products full name :
EBNA 3C
products short name :
[EBNA 3C]
products name syn :
[EBNA 3C; Epstein-Barr Virus Nuclear antigen 6]
other names :
[EBNA-3C; Epstein-Barr nuclear antigen 6; EBNA-3B; EBNA-3C; Epstein-Barr nuclear antigen 3C; EBNA-3C; EBV nuclear antigen 3C; Epstein-Barr nuclear antigen 4B]
products gene name :
[EBNA 3C]
other gene names :
[EBNA-3B/EBNA-3C; EBNA6; EBNA-6; EBV nuclear antigen 6; EBNA-3C; EBV nuclear antigen 3C; EBNA-4B]
uniprot entry name :
EBNA6_EBVB9
clonality :
Polyclonal
host :
Sheep
sequence length :
992
purity :
Ammonium Sulfate Precipitation
form :
Unconjuated. Provided as a solution in phosphate buffered saline with 0.08% sodium azide
storage stability :
Ship conditions: Room temperature. Storage : Product should be stored at -20°C . Aliquot to avoid freeze/thaw cycles. Stability: Products are stable for one year from purchase when stored properly.
tested application :
Western Blot (WB)
app notes :
Immunoblotting- Immunoprecipitates EBNA-3C when used at a dilution of 1:200
other info1 :
Immunogen: Recombinant EBNA-3C protein.
products categories :
Polyclonal Antibody; Epstein Barr Virus
products description :
EBNA-3C is a latent viral nuclear protein expressed in EBV transformed lymphoblastic cell lines and is essential for EBV mediated transformation of these cell lines. This viral nuclear protein is essential for EBV mediated positive immunoblastic lymphomas, and functions as a transcription factor.
ncbi gi num :
82503227
ncbi acc num :
YP_401671.1
ncbi gb acc num :
NC_007605.1
uniprot acc num :
P03204
uniprot summary :
Function: Plays an essential role for the activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA6 probably contributes to a negative autoregulatory control loop. Alternatively, EBNA6 also regulates the transcription of the EBV oncogene LMP1 in a cell cycle-dependent manner. It modulates the activity of several host proteins involved in cell cycle regulation including host cyclin A, MYC, RB and p27 mainly through binding to the host SCF(SKP2) complex. Ref.6. Subunit structure: Interacts with host CTPB1; this interaction seems important for EBNA6-mediated transcriptional repression. Interacts with host MYC; this interaction enhances MYC stability. Interacts (via N-terminus) with host RBPJ. Ref.3 Ref.5 Ref.7. Subcellular location: Host nucleus matrix. Note: Associated with the nuclear matrix. Ref.4. Sequence similarities: Belongs to the herpesviridae EBNA-6 family.
size1 :
0.25 mg
price1 :
340 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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