catalog number :
MBS395170
products full name :
a/b SNAP
products short name :
a/b SNAP
products name syn :
alpha/beta SNAP; mouse anti alpha/beta soluble NSF attachment protein
other names :
alpha-soluble NSF attachment protein; Alpha-soluble NSF attachment protein; alpha-soluble NSF attachment protein; alpha-SNAP; N-ethylmaleimide-sensitive factor attachment protein, alpha; N-ethylmaleimide-sensitive factor attachment protein alpha
products gene name :
a/b SNAP
other gene names :
NAPA; NAPA; SNAPA; SNAPA; SNAP-alpha
uniprot entry name :
SNAA_HUMAN
reactivity :
Human, Rat, Bovine, Chicken
form :
20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, pH 7.5
storage stability :
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
tested application :
Western Blot (WB)
other info1 :
Immunogen: Recombinant human alpha SNAP
other info2 :
Positive Control: Rat brain
products categories :
Monoclonal Antibody; Neuronal Signaling
products description :
38 kDa SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-
ncbi acc num :
NP_003818.2
ncbi gb acc num :
NM_003827.3
ncbi pathways :
Clathrin Derived Vesicle Budding Pathway (119545); Golgi Associated Vesicle Biogenesis Pathway (119546); Membrane Trafficking Pathway (106160); Synaptic Vesicle Pathway (672457); Synaptic Vesicle Cycle Pathway (373900); Synaptic Vesicle Cycle Pathway (373890); Trans-Golgi Network Vesicle Budding Pathway (106165)
ncbi summary :
This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]
uniprot summary :
Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Subunit structure: Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8 . By similarity. Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12 . By similarity. Ref.7. Subcellular location: Membrane; Peripheral membrane protein. Sequence similarities: Belongs to the SNAP family.