HRP-conjugated Sheep Anti-Human Apolipoprotein AII | MyBioSource MBS390015 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

HRP-conjugated Sheep Anti-Human Apolipoprotein AII

catalog :

MBS390015

quantity :

0.5 mL

price :

335 USD

clonality :

polyclonal

host :

sheep

conjugate :

HRP

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS390015

products type :

Antibody

products full name :

HRP-conjugated Sheep Anti-Human Apolipoprotein AII

products short name :

[Apolipoprotein AII]

products name syn :

[Horseradish Peroxidase (HRP) conjugated Sheep Anti-Human Apolipoprotein AII (Apo AII), Polyclonal Antibody]

other names :

[apolipoprotein A-II preproprotein; Apolipoprotein A-II; apolipoprotein A-II; apolipoprotein A2; apolipoprotein A-II; Apolipoprotein A2Cleaved into the following chain:Truncated apolipoprotein A-II; Alternative name(s):; Apolipoprotein A-II(1-76)]

products gene name :

[Apo AII]

other gene names :

[APOA2; APOA2; apoAII; Apo-AII; ApoA-II; Apo-AII; ApoA-II]

uniprot entry name :

APOA2_HUMAN

clonality :

Polyclonal

host :

Sheep

reactivity :

Human

specificity :

Specifically binds to human apo AII.

form :

Freeze-dried powder, restore to 0.5ml volume with distilled water.

concentration :

1mg/ml

storage stability :

Freeze-dried product should be stored refrigerated until opened. After opening, restore to 0.5 ml with distilled water. If it is not completely clear after standing for 1-2 hours at room temperature, centrifuge the product. It is stable for several weeks at 4°C as an undiluted liquid. Do not use for more than one day after dilution. For extended storage after reconstitution, we suggest the addition of an equal volume of glycerol to make a final glycerol concentration of 50% followed by storage at -20°C. The concentration of protein and buffer salts will decrease to one-half of the original after the addition of glycerol.

tested application :

Immnoblot (IB), ELISA (EIA)

app notes :

Dilution for immunoblot & ELISA range: 200 to 6,000. The antibody can be used for detection of apo AII in plasma and lipoproteins, immunoassays and immunoblots.

other info1 :

Host Note: Polyclonal sheep anti-human apo AII purified by human apo AII-Sepharose affinity column and conjugated with HRP. Preservation: In 50 mM Sodium Phosphate, 0.1M NaCl, pH 7.4 and 0.01% Thimersol. Stabilizer: 10 mg / ml Bovine Serum Albumin (BSA).

products categories :

HRP Antibodies

ncbi gi num :

4502149

ncbi acc num :

NP_001634.1

ncbi gb acc num :

NM_001643.1

uniprot acc num :

P02652

ncbi pathways :

Chylomicron-mediated Lipid Transport Pathway (106157); Complement And Coagulation Cascades Pathway (198880); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042)

ncbi summary :

This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]

uniprot summary :

Function: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Subunit structure: Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP and NDRG1. Ref.15 Ref.16 Ref.19 Ref.23. Subcellular location: Secreted. Tissue specificity: Plasma; synthesized in the liver and intestine. Post-translational modification: Met-49 is oxidized to methionine sulfoxide.Phosphorylation sites are present in the extracellular medium.Apolipoprotein A-II is O-glycosylated. Ref.22. Polymorphism: A homozygous transition at position 1 of intron 3 of APOA2 results in deficiency of apolipoprotein A-II, without significant influence either on lipid and lipoprotein profiles or on the occurrence of coronary artery disease [. MIM:107670]. Sequence similarities: Belongs to the apolipoprotein A2 family. Mass spectrometry: Molecular mass is 17252 Da from positions 24 - 100. Determined by ESI. Homodimer, without methionine sulfoxide. Ref.17Molecular mass is 17269 Da from positions 24 - 100. Determined by ESI. Homodimer, with 1 methionine sulfoxide, oxidation at Met-49. Ref.17Molecular mass is 8701.2 Da from positions 24 - 100. Determined by MALDI. Ref.18Molecular mass is 8823.4 Da from positions 24 - 100. Determined by MALDI. Cysteinylated ApoA-II. Ref.18Molecular mass is 17421.3 Da from positions 24 - 100. Determined by MALDI. Homodimer. Ref.18Molecular mass is 17293.4 Da from positions 24 - 100. Determined by MALDI. Heterodimer with truncated apolipoprotein A-II. Ref.18Molecular mass is 8578.3 Da from positions 24 - 99. Determined by MALDI. Ref.18Molecular mass is 17166.2 Da from positions 24 - 99. Determined by MALDI. Homodimer. Ref.18

size1 :

0.5 mL

price1 :

335 USD

size2 :

1 mL

price2 :

505

more info or order :

MyBioSource product webpage