HRP-conjugated Sheep Anti-Human Apolipoprotein (a) | MyBioSource MBS390007 product information

product summary

request information :

company name :

MyBioSource

product type :

antibody

product name :

HRP-conjugated Sheep Anti-Human Apolipoprotein (a)

catalog :

MBS390007

quantity :

0.5 ml

price :

320 USD

clonality :

polyclonal

host :

sheep

conjugate :

HRP

reactivity :

human

application :

enzyme immunoassay, western blot, ELISA

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS390007

products type :

Antibody

products full name :

HRP-conjugated Sheep Anti-Human Apolipoprotein (a)

products short name :

Apolipoprotein (a)

products name syn :

Horseradish Peroxidase (HRP) conjugated Sheep Anti-Human Apolipoprotein (a) [Apo (a)], Polyclonal Antibody

other names :

apolipoprotein; Apolipoprotein A-II; apolipoprotein A-II; apolipoprotein A2; apolipoprotein A-II; Apolipoprotein A2Cleaved into the following chain:Truncated apolipoprotein A-II; Alternative name(s):; Apolipoprotein A-II(1-76)

other gene names :

APOA2; APOA2; apoAII; Apo-AII; ApoA-II; Apo-AII; ApoA-II

uniprot entry name :

APOA2_HUMAN

clonality :

polyclonal

host :

Sheep

sequence length :

100

specificity :

Specifically binds to human Lp (a) and apo (a). Dilution for immunoblot and ELISA range: 200 to 8,000.

form :

0.5 ml in Freeze-dried powder.

concentration :

0.8 mg / ml

storage stability :

Freeze-dried product should be stored refrigerated until opened. After opening, restore to 0.5 ml with distilled water. If it is not completely clear after standing for 1-2 Hours at room temperature, centrifuge the product. It is stable for several weeks at 4 degree C as an undiluted liquid. Do not use for more than one day after dilution. For extended storage after reconstitution, we suggest aliquot to avoid repeated freezing and thawing; or the addition of an equal volume of glycerol to make a final glycerol concentration of 50%, followed by storage at -20 degree C. The concentration of protein and buffer salts will decrease to one-half of the original after the addition of glycerol

tested application :

ELISA (EIA), Immunoblot (IB)

app notes :

Freeze-dried powder. Dilution for Immunoblot & ELISA range: 1,000 to 8,000. Use: The antibody can be used to detect the existence of Lp (a) and apo (a) in plasma and lipoproteins; for immunoassay and immunoblot.

other info1 :

Source Note: Polyclonal antibody purified by human apo (a)-Sepharose and conjugated with HRP. (Cross reactivity to plasminogen was removed by passing plasminogen-Sepharose prior to apo (a)-Sepharose purification.).

other info2 :

Preservative: 50 mM PBS, 0.1 M NaCl, pH 7.4 and 0.01% Thimersol. Stabilizer: 10 mg / ml Bovine Serum Albumin.

products categories :

HRP Antibodies

ncbi gi num :

671882

ncbi acc num :

CAA28583.1

uniprot acc num :

P02652

ncbi mol weight :

11,175 Da

ncbi pathways :

Chylomicron-mediated Lipid Transport Pathway 106157!!Complement And Coagulation Cascades Pathway 198880!!Disease Pathway 530764!!Diseases Associated With Visual Transduction Pathway 771581!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Lipid Digestion, Mobilization, And Transport Pathway 106111!!Lipoprotein Metabolism Pathway 106156!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!PPAR Signaling Pathway 83042

ncbi summary :

This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]

uniprot summary :

Function: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Subunit structure: Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP and NDRG1. Ref.15 Ref.16 Ref.19 Ref.23. Subcellular location: Secreted. Tissue specificity: Plasma; synthesized in the liver and intestine. Post-translational modification: Met-49 is oxidized to methionine sulfoxide.Phosphorylation sites are present in the extracellular medium.Apolipoprotein A-II is O-glycosylated. Ref.22. Polymorphism: A homozygous transition at position 1 of intron 3 of APOA2 results in deficiency of apolipoprotein A-II, without significant influence either on lipid and lipoprotein profiles or on the occurrence of coronary artery disease [. MIM:107670]. Sequence similarities: Belongs to the apolipoprotein A2 family. Mass spectrometry: Molecular mass is 17252 Da from positions 24 - 100. Determined by ESI. Homodimer, without methionine sulfoxide. Ref.17Molecular mass is 17269 Da from positions 24 - 100. Determined by ESI. Homodimer, with 1 methionine sulfoxide, oxidation at Met-49. Ref.17Molecular mass is 8701.2 Da from positions 24 - 100. Determined by MALDI. Ref.18Molecular mass is 8823.4 Da from positions 24 - 100. Determined by MALDI. Cysteinylated ApoA-II. Ref.18Molecular mass is 17421.3 Da from positions 24 - 100. Determined by MALDI. Homodimer. Ref.18Molecular mass is 17293.4 Da from positions 24 - 100. Determined by MALDI. Heterodimer with truncated apolipoprotein A-II. Ref.18Molecular mass is 8578.3 Da from positions 24 - 99. Determined by MALDI. Ref.18Molecular mass is 17166.2 Da from positions 24 - 99. Determined by MALDI. Homodimer. Ref.18

size :

0.5 ml

price :

320 USD

more info or order :

MyBioSource product webpage