FITC-conjugated Sheep Anti-Human Apolipoprotein (a) | MyBioSource MBS390005 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

FITC-conjugated Sheep Anti-Human Apolipoprotein (a)

catalog :

MBS390005

quantity :

0.5 ml

price :

350 USD

clonality :

polyclonal

host :

sheep

conjugate :

FITC

reactivity :

human

application :

immunocytochemistry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS390005

products type :

Antibody

products full name :

FITC-conjugated Sheep Anti-Human Apolipoprotein (a)

products short name :

Apolipoprotein (a)

products name syn :

FITC conjugated Sheep Anti-Human Apolipoprotein (a) [Apo (a)], Polyclonal Antibody

other names :

apolipoprotein; Apolipoprotein A-II; apolipoprotein A-II; apolipoprotein A2; apolipoprotein A-II; Apolipoprotein A2Cleaved into the following chain:Truncated apolipoprotein A-II; Alternative name(s):; Apolipoprotein A-II(1-76)

other gene names :

APOA2; APOA2; apoAII; Apo-AII; ApoA-II; Apo-AII; ApoA-II

uniprot entry name :

APOA2_HUMAN

host :

Sheep

sequence length :

100

specificity :

Specifically binds to human apo (a). Molar F/P ratio is 5.7. The investigator should determine working dilutions.

form :

0.5 ml in Freeze-dried powder

concentration :

1 mg / ml

storage stability :

Freeze-dried product should be refrigerated until opened. After opening, restore to 0.5 ml with distilled water. If it is not completely clear after standing for 1-2 hours at room temperature, centrifuge the product. It is stable for several weeks at 4 degree C as an undiluted liquid. Do not use for more than one day after dilution. The products are light sensitive and should be keep in dark. To avoid repeated freezing and thawing after reconstitution, we suggest aliquots and storage at -20 degree C.

tested application :

Immunofluorescence (IF)

app notes :

Molar F/P Ratio: 5.7. Freeze-dried powder. Use: The antibody can be used to detect the existence of human apo (a) with immuno-fluoroscent approach.

other info1 :

Source Note: Polyclonal antibody purified by human apo (a)-Sepharose and labeled with FITC. (Cross reactivity to plasminogen was removed by passing plasminogen-Sepharose prior to apo (a)-Sepharose purification.).

other info2 :

Preservative: 75 mM PBS, 75 mM NaCl, 0.5 mM EDTA, 0.02% NaN3, pH 7.4. Stabilizer: 5 mg / ml Bovine Serum Albumin

products categories :

FITC Antibodies

ncbi gi num :

671882

ncbi acc num :

CAA28583.1

uniprot acc num :

P02652

ncbi mol weight :

11,175 Da

ncbi pathways :

Chylomicron-mediated Lipid Transport Pathway 106157!!Complement And Coagulation Cascades Pathway 198880!!Disease Pathway 530764!!Diseases Associated With Visual Transduction Pathway 771581!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Lipid Digestion, Mobilization, And Transport Pathway 106111!!Lipoprotein Metabolism Pathway 106156!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!PPAR Signaling Pathway 83042

ncbi summary :

This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]

uniprot summary :

Function: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Subunit structure: Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP and NDRG1. Ref.15 Ref.16 Ref.19 Ref.23. Subcellular location: Secreted. Tissue specificity: Plasma; synthesized in the liver and intestine. Post-translational modification: Met-49 is oxidized to methionine sulfoxide.Phosphorylation sites are present in the extracellular medium.Apolipoprotein A-II is O-glycosylated. Ref.22. Polymorphism: A homozygous transition at position 1 of intron 3 of APOA2 results in deficiency of apolipoprotein A-II, without significant influence either on lipid and lipoprotein profiles or on the occurrence of coronary artery disease [. MIM:107670]. Sequence similarities: Belongs to the apolipoprotein A2 family. Mass spectrometry: Molecular mass is 17252 Da from positions 24 - 100. Determined by ESI. Homodimer, without methionine sulfoxide. Ref.17Molecular mass is 17269 Da from positions 24 - 100. Determined by ESI. Homodimer, with 1 methionine sulfoxide, oxidation at Met-49. Ref.17Molecular mass is 8701.2 Da from positions 24 - 100. Determined by MALDI. Ref.18Molecular mass is 8823.4 Da from positions 24 - 100. Determined by MALDI. Cysteinylated ApoA-II. Ref.18Molecular mass is 17421.3 Da from positions 24 - 100. Determined by MALDI. Homodimer. Ref.18Molecular mass is 17293.4 Da from positions 24 - 100. Determined by MALDI. Heterodimer with truncated apolipoprotein A-II. Ref.18Molecular mass is 8578.3 Da from positions 24 - 99. Determined by MALDI. Ref.18Molecular mass is 17166.2 Da from positions 24 - 99. Determined by MALDI. Homodimer. Ref.18

size :

0.5 ml

price :

350 USD

more info or order :

MyBioSource product webpage