product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD3epsilon
catalog :
MBS378111
quantity :
0.5 mg
price :
330 USD
clonality :
monoclonal
host :
unidentified
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS378111
products type :
Antibody
products full name :
CD3epsilon
products short name :
[CD3epsilon]
products name syn :
[AI504783;  CD3; CD3epsilon; T3e]
other names :
[CD3epsilon; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; CD3 antigen, epsilon polypeptide; T-cell surface antigen T3/Leu-4 epsilon chain; CD_antigen: CD3e]
products gene name :
[CD3epsilon]
other gene names :
[Cd3e; Cd3e; CD3; T3e; AI504783; CD3epsilon]
clonality :
Monoclonal
isotype :
Armenian hamster IgG
host :
unknown
sequence length :
181
purity :
>95%
form :
PBS, pH7
concentration :
2mg/ml
storage stability :
For long term storage, aliquot and store at -20°C frozen. Avoid repeated freeze-thaw cycles. For use within 30 days store at 4°C.
tested application :
T cell depletion T cell activation; Immunofluorescence; Flow cytometry; Western blot
other info1 :
Preservative: None. Total protein: 500ug. Endotoxin: <2EU/mg. Sterile: 0.2um filtration
other info2 :
Production: Purified by protein G from tissue culture supernatant. Preservatives: No preservatives.
ncbi gi num :
126362122
ncbi acc num :
ABO10203.1
ncbi pathways :
Adaptive Immune System Pathway (1367473); Chagas Disease (American Trypanosomiasis) Pathway (147810); Chagas Disease (American Trypanosomiasis) Pathway (147795); Costimulation By The CD28 Family Pathway (1367479); Downstream TCR Signaling Pathway (1367478); Generation Of Second Messenger Molecules Pathway (1367477); HTLV-I Infection Pathway (373903); HTLV-I Infection Pathway (373889); Hematopoietic Cell Lineage Pathway (83275); Hematopoietic Cell Lineage Pathway (489)
uniprot summary :
CD3E: a T cell surface glycoprotein that is a component of the T cell antigen receptor. The recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Contains 1 immunoglobulin-like domain and 1 ITAM domain. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 9 A5.2 9 24.84 cM. Cellular Component: alpha-beta T cell receptor complex; dendritic spine; external side of plasma membrane; immunological synapse; intercellular junction; plasma membrane; T cell receptor complex. Molecular Function: protein binding; protein heterodimerization activity; protein homodimerization activity; SH3 domain binding; signal transducer activity. Biological Process: cell surface receptor linked signal transduction; cerebellum development; dendrite development; lymphocyte activation; negative regulation of smoothened signaling pathway; negative thymic T cell selection; positive regulation of alpha-beta T cell proliferation; positive regulation of calcium-mediated signaling; positive regulation of interferon-gamma production; positive regulation of interleukin-2 biosynthetic process; positive regulation of interleukin-4 production; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of T cell activation; positive regulation of T cell anergy; positive regulation of T cell proliferation; protein homooligomerization; response to nutrient; T cell costimulation; T cell receptor signaling pathway
size1 :
0.5 mg
price1 :
330 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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