product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Anti-Neurocan [650.24]
catalog :
MBS375211
quantity :
0.05 mL
price :
370 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
650.24
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS375211
products type :
Antibody
products full name :
Mouse Anti-Neurocan [650.24]
products short name :
Neurocan
products name syn :
Chondroitin sulfate proteoglycan 3 antibody; Cspg3 antibody; NCAN antibody; NEUR antibody; Neurocan coreprotein antibody; Neurocan antibody
other names :
neurocan core protein; Neurocan core protein; neurocan core protein; chondroitin sulfate proteoglycan 3 (neurocan); neurocan proteoglycan; neurocan; Chondroitin sulfate proteoglycan 3
other gene names :
NCAN; NCAN; CSPG3; CSPG3; NEUR
uniprot entry name :
NCAN_HUMAN
clonality :
Monoclonal
isotype :
IgG
clone :
650.24
host :
Mouse
reactivity :
Mouse, Rat, Human
sequence length :
1321
specificity :
Specific for Neurocan core protein; also reacts with neurocan C fragment
purity :
Protein G
form :
Purified antibody (from supernatant) containing PBS 0.1% sodium azide;
concentration :
1mg/ml
tested application :
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB)
app notes :
Optimal antibody dilution should be determined by titration, however as a guideline try; WB: Use at an assay dependent dilution. Predicted molecular weight: 143 kDa
other info1 :
Target Antigen: Neurocan. Immunogen: Embryonic rat brain proteoglycans
other info2 :
Myeloma/fusion Partners: P3X myeloma
ncbi gi num :
118600983
ncbi acc num :
NP_004377.2
ncbi gb acc num :
NM_004386.2
uniprot acc num :
O14594
ncbi mol weight :
143,093 Da
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); Axon Guidance Pathway (105688); CS/DS Degradation Pathway (645311); Chondroitin Sulfate Biosynthesis Pathway (645309); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Defective B3GAT3 Causes JDSSDHD Pathway (1127588); Defective B4GALT7 Causes EDS, Progeroid Type Pathway (1127587); Defective CHST14 Causes EDS, Musculocontractural Type Pathway (1127591); Defective CHST3 Causes SEDCJD Pathway (1127590); Defective CHSY1 Causes TPBS Pathway (1127589)
ncbi summary :
Neurocan is a chondroitin sulfate proteoglycan thought to be involved in the modulation of cell adhesion and migration.[supplied by OMIM, Jul 2002]
uniprot summary :
CSPG3: May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid. Belongs to the aggrecan/versican proteoglycan family. Protein type: Secreted, signal peptide; Secreted; Cell adhesion. Chromosomal Location of Human Ortholog: 19p12. Cellular Component: lysosomal lumen; proteinaceous extracellular matrix; Golgi lumen; extracellular region. Molecular Function: extracellular matrix structural constituent; hyaluronic acid binding; calcium ion binding; carbohydrate binding. Biological Process: chondroitin sulfate metabolic process; axon guidance; extracellular matrix organization and biogenesis; central nervous system development; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; chondroitin sulfate catabolic process; regulation of synapse structural plasticity; pathogenesis; cell adhesion; skeletal development; dermatan sulfate biosynthetic process
size1 :
0.05 mL
price1 :
370 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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